Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

Pseudomonas aeruginosa is an opportunistic human pathogen characterized by an innate
resistance to multiple antimicrobial agents. A major contribution to this intrinsic multidrug …

Objectives: Multidrug efflux pumps are thought to be involved in mediating multidrug
resistance in Pseudomonas aeruginosa. Here we aim to characterize hitherto …

Pseudomonas aeruginosa is an opportunistic human pathogen exhibiting innate resistance
to multiple antimicrobial agents. This intrinsic multidrug resistance is caused by synergy …

We have earlier described mexA-mexB-oprK, an operon involved in pyoverdine export in
Pseudomonas aeruginosa, and suggested that the products of these genes also contribute …

Abstract MexAB-OprM and MexEF-OprN are Pseudomonas aeruginosa efflux pumps
involved in the development of antibiotic resistance. Several studies developed with …

Gram‐negative bacteria remain clinically important pathogens in both hospital and
community settings. Recent research indicates that efflux pumps play a prominent role in the …

Pseudomonas aeruginosa expresses a low level of the MexAB-OprM efflux pump and
shows natural resistance to many structurally and functionally diverse antibiotics. The …

Therapeutic failures against diseases due to resistant Gram-negative bacteria have become
a major threat nowadays as confirmed by surveillance reports across the world. One of the …

Efflux pump systems are one of the most important mechanisms conferring multidrug
resistance in Pseudomonas aeruginosa. MexAB-OprM efflux pump is one of the largest multi …