Over 300 posttranslational modifications (PTMs) are known to modify the functions of
proteins by affecting processes ranging from activation, degradation, localization, secretion …

PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity,
transcription, and DNA replication stress management. However, little is known about the …

Protein ADP-ribosylation plays important but ill-defined roles in antiviral signalling cascades
such as the interferon response. Several viruses of clinical interest, including coronaviruses …

Poly (ADP-ribose) polymerase 7 (PARP-7) has emerged as a critically important member of
a large enzyme family that catalyzes ADP-ribosylation in mammalian cells. PARP-7 is a …

Transcriptome analyses have recently identified PARP12, a member of a large family of ADP-
ribosyl transferases, as an interferon-induced gene (ISG), whose function remains …

Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …

Poly-adenosine diphosphate-ribose polymerase (PARP) implements posttranslational mono-
or poly-ADP-ribosylation modification of target proteins. Among the known 18 members in …

Innate immune cells are critical in protective immunity against viral infections, involved in
sensing foreign viral nucleic acids. Here we report that the poly (ADP-ribose) polymerase 9 …

PARP-catalysed ADP-ribosylation (ADPr) is important in regulating various cellular
pathways. Until recently, PARP-dependent mono-ADP-ribosylation has been poorly …

ADP ribosylation has been recently recognised as an important posttranslational
modification regulating numerous cellular processes. This enzymatic activity is shared by …