Distributed coding of choice, action and engagement across the mouse brain

NA Steinmetz, P Zatka-Haas, M Carandini, KD Harris - Nature, 2019 - nature.com
Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

[HTML][HTML] Brain-wide dynamics linking sensation to action during decision-making

A Khilkevich, M Lohse, R Low, I Orsolic, T Bozic… - Nature, 2024 - nature.com
Perceptual decisions rely on learned associations between sensory evidence and
appropriate actions, involving the filtering and integration of relevant inputs to prepare and …

Dissociated functional significance of decision-related activity in the primate dorsal stream

LN Katz, JL Yates, JW Pillow, AC Huk - Nature, 2016 - nature.com
During decision making, neurons in multiple brain regions exhibit responses that are
correlated with decisions,,,,,. However, it remains uncertain whether or not various forms of …

Synaptic wiring motifs in posterior parietal cortex support decision-making

AT Kuan, G Bondanelli, LN Driscoll, J Han, M Kim… - Nature, 2024 - nature.com
The posterior parietal cortex exhibits choice-selective activity during perceptual decision-
making tasks,,,,,,,,–. However, it is not known how this selective activity arises from the …

Representation of a perceptual decision in developing oculomotor commands

JI Gold, MN Shadlen - Nature, 2000 - nature.com
Behaviour often depends on the ability to make categorical judgements about sensory
information acquired over time. Such judgements require a comparison of the evidence …

Decision-related activity in sensory neurons reflects more than a neuron's causal effect

H Nienborg, BG Cumming - Nature, 2009 - nature.com
During perceptual decisions, the activity of sensory neurons correlates with a subject's
percept, even when the physical stimulus is identical,,,,,,,,. The origin of this correlation is …

Frontal cortex neuron types categorically encode single decision variables

J Hirokawa, A Vaughan, P Masset, T Ott, A Kepecs - Nature, 2019 - nature.com
Individual neurons in many cortical regions have been found to encode specific, identifiable
features of the environment or body that pertain to the function of the region,–. However, in …

Shared mechanisms underlie the control of working memory and attention

MF Panichello, TJ Buschman - Nature, 2021 - nature.com
Cognitive control guides behaviour by controlling what, when, and how information is
represented in the brain. For example, attention controls sensory processing; top-down …

Single-neuron perturbations reveal feature-specific competition in V1

SN Chettih, CD Harvey - Nature, 2019 - nature.com
The computations performed by local neural populations, such as a cortical layer, are
typically inferred from anatomical connectivity and observations of neural activity. Here we …

The importance of mixed selectivity in complex cognitive tasks

M Rigotti, O Barak, MR Warden, XJ Wang, ND Daw… - Nature, 2013 - nature.com
Single-neuron activity in the prefrontal cortex (PFC) is tuned to mixtures of multiple task-
related aspects. Such mixed selectivity is highly heterogeneous, seemingly disordered and …