Chromatin fibers must fold or coil in the process of chromosome condensation. Patterns of
coiling have been demonstrated for reconstituted chromatin, but the actual trajectories of …

Although the formation of 30-nm chromatin fibers is thought to be the most basic event of
chromatin compaction, it remains controversial because high-resolution imaging of …

Mitotic chromosomes are essential structures for the faithful transmission of replicated
genomic DNA into two daughter cells during cell division. A long strand of DNA is wrapped …

How is a long strand of genomic DNA packaged into a mitotic chromosome or nucleus? The
nucleosome fiber (beads-on-a-string), in which DNA is wrapped around core histones, has …

Chromatin fibers have been observed and measured in frozen hydrated sections of three
types of cell (chicken erythrocytes and sperm of Patiria miniata and Thyone briareus) …

Three classes of chicken erythrocyte chromatin particles differing in their content of lysine-
rich histones and/or spacer DNA have been studied in order to determine their ability to …

The predominant view of chromatin structure is that the beaded chain of nucleosomes is
folded into a symmetrical helical fibre. Recently, however, direct evidence from cryoelectron …

The higher-order assembly of the approximately 30 nm chromatin fibers into the
characteristic morphology of HeLa mitotic chromosomes was investigated by electron …

A long strand of DNA is wrapped around the core histone and forms a nucleosome.
Although the nucleosome has long been assumed to be folded into 30-nm chromatin fibres …

The arrangement of the nucleosome-containing DNA fibers of chromosomes in mitotic HeLa
cells was studied by thin sectioning and electron microscopy. Thin sections of mitotic cells …