Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

M Hasegawa, H Kishino, T Yano - Journal of molecular evolution, 1985 - Springer
A new statistical method for estimating divergence dates of species from DNA sequence
data by a molecular clock approach is developed. This method takes into account effectively …

Man's place in Hominoidea as inferred from molecular clocks of DNA

M Hasegawa, H Kishino, T Yano - Journal of Molecular Evolution, 1987 - Springer
Divergence dates among primates were estimated by molecular clock analysis of DNA
sequence data. A molecular clock of η-globin pseudogene was calibrated by setting the date …

Time of the deepest root for polymorphism in human mitochondrial DNA

M Hasegawa, S Horai - Journal of Molecular Evolution, 1991 - Springer
A molecular clock analysis was carried out on the nucleotide sequences of parts of the major
noncoding region of mitochondrial DNA (mtDNA) from the major geographic populations of …

Estimation of primate speciation dates using local molecular clocks

AD Yoder, Z Yang - Molecular biology and evolution, 2000 - academic.oup.com
Protein-coding genes of the mitochondrial genomes from 31 mammalian species were
analyzed to estimate the speciation dates within primates and also between rats and mice …

Estimation of branching dates among primates by molecular clocks of nuclear DNA which slowed down in Hominoidea

M Hasegawa, H Kishino, T Yano - Journal of Human Evolution, 1989 - Elsevier
As there is evidence that the nucleotide substitution rate of globin gene region in nuclear
DNA has decreased in Hominoidea compared to Cercopithecoidea, we have developed a …

Mitochondrial DNA evolution in primates: transition rate has been extremely low in the lemur

M Hasegawa, H Kishino, K Hayasaka… - Journal of molecular …, 1990 - Springer
Based on mitochondrial DNA (mt-DNA) sequence data from a wide range of primate
species, branching order in the evolution of primates was inferred by the maximum …

Molecular timing of primate divergences as estimated by two nonprimate calibration points

U Arnason, A Gullberg, A Janke - Journal of Molecular Evolution, 1998 - Springer
The complete mitochondrial DNA (mtDNA) molecule of the hamadryas baboon, Papio
hamadryas, was sequenced and included in a molecular analysis of 24 complete …

Toward a more accurate time scale for the human mitochondrial DNA tree

M Hasegawa, A Di Rienzo, TD Kocher… - Journal of molecular …, 1993 - Springer
Several estimates of the time of occurrence of the most recent common mitochondrial DNA
(mtDNA) ancestor of modern humans have been made. Estimates derived from noncoding …

A new molecular clock of mitochondrial DNA and the evolution of Hominoids

M Hasegawa, T Yano, H Kishino - … of the Japan Academy, series B, 1984 - jstage.jst.go.jp
The approximate constancy of the rate of change is one feature of molecular evolution. It is
consistent with the neutral theory1 and serves as a clock to date a divergence time of …

Improved dating of the human/chimpanzee separation in the mitochondrial DNA tree: heterogeneity among amino acid sites

J Adachi, M Hasegawa - Journal of Molecular Evolution, 1995 - Springer
The internal branch lengths estimated by distance methods such as neighbor joining are
shown to be biased to be short when the evolutionary rate differs among sites. The variable …