Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses
in the central nervous system. The head of the spine is connected to the dendritic shaft by a …

Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic
component of most excitatory synapses in the brain. They play critical roles in synaptic …

The structure of dendritic spines determines synaptic efficacy, a plastic process that
mediates information processing in the vertebrate nervous system. Aberrant spine …

Neurons are perpetually receiving vast amounts of information in the form of synaptic input
from surrounding cells. The majority of input occurs at thousands of dendritic spines, which …

Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are
located. Recent advances in imaging technologies have given us great insight into the …

Dendritic spines have been proposed to transform synaptic signals through chemical and
electrical compartmentalization. However, the quantitative contribution of spine morphology …

Dendritic spines are cellular specializations that greatly increase the connectivity of neurons
and modulate the “weight” of most postsynaptic excitatory potentials. Spines are found in …

The majority of fast excitatory synaptic transmission in the central nervous system takes
place at protrusions along dendrites called spines. Dendritic spines are highly …

The geometry of dendritic spines has a major impact on signal transmission at excitatory
synapses. To study it in detail we raised transgenic mice expressing an intrinsic green …

Psychiatric and neurologic disorders ranging from mental retardation to addiction are
accompanied by structural and functional alterations of synaptic connections in the brain …