Calcific deposits in porcine bioprostheses: structure and pathogenesis

VJ Ferrans, SW Boyce, ME Billingham, M Jones… - The American journal of …, 1980 - Elsevier
Gross, histologic and ultrastructural studies were made of 14 porcine valve bioprostheses
that were found to contain calcific deposits at the time of removal either at reoperation (13 …

Cardiovascular implant calcification: a survey and update

RJ Levy, FJ Schoen, HC Anderson, H Harasaki… - Biomaterials, 1991 - Elsevier
Calcification of cardiovascular prosthetic implants is a common and important problem. This
review provides an update based upon the Conference on Cardiovascular Implant …

Calcification of porcine prosthetic heart valves: a radiographic and light microscopy study.

PR Cipriano, ME Billingham, PE Oyer, LM Kutsche… - Circulation, 1982 - Am Heart Assoc
To determine the incidence and extent of calcification of implanted glutaraldehyde-treated
porcine prosthetic heart valves, 82 valves explanted from 73 patients were examined for …

Calcification of bovine pericardium used in cardiac valve bioprostheses. Implications for the mechanisms of bioprosthetic tissue mineralization.

FJ Schoen, JW Tsao, RJ Levy - The American journal of pathology, 1986 - ncbi.nlm.nih.gov
Calcification of bioprosthetic heart valves fabricated from glutaraldehyde-pretreated bovine
pericardium has not been investigated. The objectives of this study were to characterize …

Onset and progression of experimental bioprosthetic heart valve calcification.

FJ Schoen, RJ Levy, AC Nelson… - … ; a journal of technical …, 1985 - europepmc.org
Calcification, the major cause of bioprosthetic heart valve failures, is a serious clinical
problem with uncertain pathogenesis. The objectives of the present study were to define the …

Calcific degeneration as the main cause of porcine bioprosthetic valve failure

A Milano, U Bortolotti, E Talenti, C Valfrè… - The American journal of …, 1984 - Elsevier
Sixty-seven glutaraldehyde-processed porcine bioprostheses (PBs), recovered at autopsy or
reoperation from 65 patients, were evaluated by roentgenologic and pathologic …

[HTML][HTML] Dynamic in vitro calcification of bioprosthetic porcine valves: evidence of apatite crystallization

E Pettenazzo, M Deiwick, G Thiene, G Molin… - The Journal of Thoracic …, 2001 - Elsevier
Objective: Calcification is the most important cause of structural deterioration of
glutaraldehyde-fixed bioprosthetic valves. Devitalization of tissue favors calcium deposits in …

Calcification in porcine xenograft valves in children

MM Silver, J Pollock, MD Silver, WG Williams… - The American Journal of …, 1980 - Elsevier
Calcification developed in the degenerating collagen of the cusps of three porcine xenograft
heart valves implanted in children for less than 4 years. The morphologic features and …

Calcification of cardiac valve bioprostheses: biochemical, histologic, and ultrastructural observations in a subcutaneous implantation model system

MC Fishbein, RJ Levy, VJ Ferrans, LC Dearden… - The Journal of Thoracic …, 1982 - Elsevier
To study the process of calcification in bioprostheses, 108 glutaraldehyde-treated porcine
aortic valve leaflets were implanted subcutaneously in rabbits and removed 1 day to 6 …

Physicochemical properties of calcific deposits isolated from porcine bioprosthetic heart valves removed from patients following 2–13 years function

BB Tomazic, WE Brown… - Journal of biomedical …, 1994 - Wiley Online Library
The purpose of this study was to characterize the physicochemical properties of calcific
deposits that cause the failure of tissue‐derived heart valve bioprostheses. This was done in …