Lateral orbitofrontal neurons acquire responses to upshifted, downshifted, or blocked cues during unblocking

N Lopatina, MA McDannald, CV Styer, BF Sadacca… - Elife, 2015 - elifesciences.org
The lateral orbitofrontal cortex (lOFC) has been described as signaling either outcome
expectancies or value. Previously, we used unblocking to show that lOFC neurons respond …

Orbitofrontal neurons acquire responses to 'valueless' Pavlovian cues during unblocking

MA McDannald, GR Esber, MA Wegener, HM Wied… - Elife, 2014 - elifesciences.org
The orbitofrontal cortex (OFC) has been described as signaling outcome expectancies or
value. Evidence for the latter comes from the studies showing that neural signals in the OFC …

Medial orbitofrontal neurons preferentially signal cues predicting changes in reward during unblocking

N Lopatina, MA McDannald, CV Styer… - Journal of …, 2016 - Soc Neuroscience
The orbitofrontal cortex (OFC) has been broadly implicated in the ability to use the current
value of expected outcomes to guide behavior. Although value correlates have been …

Subpopulations of neurons in lOFC encode previous and current rewards at time of choice

DL Hocker, CD Brody, C Savin, CM Constantinople - Elife, 2021 - elifesciences.org
Studies of neural dynamics in lateral orbitofrontal cortex (lOFC) have shown that subsets of
neurons that encode distinct aspects of behavior, such as value, may project to common …

Functional heterogeneity within the rodent lateral orbitofrontal cortex dissociates outcome devaluation and reversal learning deficits

MC Panayi, S Killcross - Elife, 2018 - elifesciences.org
The orbitofrontal cortex (OFC) is critical for updating reward-directed behaviours flexibly
when outcomes are devalued or when task contingencies are reversed. Failure to update …

Basolateral amygdala to orbitofrontal cortex projections enable cue-triggered reward expectations

NT Lichtenberg, ZT Pennington, SM Holley… - Journal of …, 2017 - Soc Neuroscience
To make an appropriate decision, one must anticipate potential future rewarding events,
even when they are not readily observable. These expectations are generated by using …

Cracking and packing information about the features of expected rewards in the orbitofrontal cortex

A Shimbo, YK Takahashi, AJ Langdon… - Journal of …, 2024 - jneurosci.org
The orbitofrontal cortex (OFC) is crucial for tracking various aspects of expected outcomes,
thereby helping to guide choices and support learning. Our previous study showed that the …

Increased firing to cues that predict low-value reward in the medial orbitofrontal cortex

AC Burton, V Kashtelyan, DW Bryden… - Cerebral …, 2014 - academic.oup.com
Anatomical, imaging, and lesion work have suggested that medial and lateral aspects of
orbitofrontal cortex (OFC) play different roles in reward-guided decision-making, yet few …

Rat orbitofrontal cortex separately encodes response and outcome information during performance of goal-directed behavior

T Furuyashiki, PC Holland… - Journal of Neuroscience, 2008 - Soc Neuroscience
Orbitofrontal cortex (OFC) neurons encode rewards and the cues that predict them,
providing a neural substrate for outcome expectancy, an important component of goal …

Neural estimates of imagined outcomes in basolateral amygdala depend on orbitofrontal cortex

F Lucantonio, MPH Gardner, A Mirenzi… - Journal of …, 2015 - Soc Neuroscience
Reciprocal connections between the orbitofrontal cortex (OFC) and the basolateral nucleus
of the amygdala (BLA) provide a critical circuit for guiding normal behavior when information …