Cellulose deconstruction can be achieved by three distinct enzymatic paradigms: free
enzymes, multifunctional enzymes, and self‐assembled, multi‐enzyme complexes …

Background Microorganisms employ a multiplicity of enzymes to efficiently degrade the
composite structure of plant cell wall cellulosic polysaccharides. These remarkable enzyme …

Cellulosomes are multi-enzyme complexes produced by certain anaerobic bacteria that
exhibit efficient degradation of plant cell wall polysaccharides. To understand their …

We have been developing the cellulases of Thermobifida fusca as a model to explore the
conversion from a free cellulase system to the cellulosomal mode. Three of the six T. fusca …

Degradation of cellulose is of major interest in the quest for alternative sources of renewable
energy, for its positive effects on environment and ecology, and for use in advanced …

Conversion of components of the Thermobifida fusca free-enzyme system to the
cellulosomal mode using the designer cellulosome approach can be employed to discover …

Cellulosomes are efficient cellulose-degradation systems produced by selected anaerobic
bacteria. This multi-enzyme complex is assembled from a group of cellulases attached to a …

During the course of our studies on the structure–function relationship of cellulosomes, we
were interested in converting the free cellulase system of the aerobic bacterium …

Cellulose recalcitrance toward saccharification is a barrier for low-cost biofuels production.
Ammonia-based pretreatments can alter the native cellulose-I allomorphic state to form an …

Detailed understanding of cell wall degrading enzymes is important for their modeling and
industrial applications, including in the production of biofuels. Here we used Cel9A, a …