Sex-Induced Silencing Operates During Opposite-Sex and Unisexual Reproduction in Cryptococcus neoformans

X Wang, S Darwiche, J Heitman - Genetics, 2013 - academic.oup.com
Cryptococcus neoformans is a human fungal pathogen that undergoes a dimorphic
transition from yeast to hyphae during a-α opposite-sex mating and α-α unisexual …

Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi

X Wang, YP Hsueh, W Li, A Floyd… - Genes & …, 2010 - genesdev.cshlp.org
Cosuppression is a silencing phenomenon triggered by the introduction of homologous
DNA sequences into the genomes of organisms as diverse as plants, fungi, flies, and …

Sexual Reproduction of Cryptococcus

YP Hsueh, X Lin, KJ Kwon‐Chung… - … : from human pathogen …, 2010 - Wiley Online Library
This chapter reviews the discovery of both opposite‐sex and unisexual reproduction and
illustrates how these pathways are molecularly controlled and the central cell biology …

Pheromone independent unisexual development in Cryptococcus neoformans

R Gyawali, Y Zhao, J Lin, Y Fan, X Xu… - PLoS …, 2017 - journals.plos.org
The fungus Cryptococcus neoformans can undergo a-α bisexual and unisexual
reproduction. Completion of both sexual reproduction modes requires similar cellular …

Transcription Factors Mat2 and Znf2 Operate Cellular Circuits Orchestrating Opposite- and Same-Sex Mating in Cryptococcus neoformans

X Lin, JC Jackson, M Feretzaki, C Xue, J Heitman - PLoS genetics, 2010 - journals.plos.org
Cryptococcus neoformans is a human fungal pathogen that undergoes a dimorphic
transition from a unicellular yeast to multicellular hyphae during opposite sex (mating) and …

Unisexual versus bisexual mating in Cryptococcus neoformans: Consequences and biological impacts

C Fu, S Sun, RB Billmyre, KC Roach… - Fungal Genetics and …, 2015 - Elsevier
Cryptococcus neoformans is an opportunistic human fungal pathogen and can undergo both
bisexual and unisexual mating. Despite the fact that one mating type is dispensable for …

Mating-Type Locus of Cryptococcus neoformans: a Step in the Evolution of Sex Chromosomes

KB Lengeler, DS Fox, JA Fraser, A Allen… - Eukaryotic …, 2002 - Am Soc Microbiol
The sexual development and virulence of the fungal pathogen Cryptococcus neoformans is
controlled by a bipolar mating system determined by a single locus that exists in two alleles …

Unisexual Reproduction Drives Meiotic Recombination and Phenotypic and Karyotypic Plasticity in Cryptococcus neoformans

S Sun, RB Billmyre, PA Mieczkowski, J Heitman - PLoS Genetics, 2014 - journals.plos.org
In fungi, unisexual reproduction, where sexual development is initiated without the presence
of two compatible mating type alleles, has been observed in several species that can also …

Transgene Induced Co-Suppression during Vegetative Growth in Cryptococcus neoformans

X Wang, P Wang, S Sun, S Darwiche, A Idnurm… - 2012 - journals.plos.org
Introduction of DNA sequences into the genome often results in homology-dependent gene
silencing in organisms as diverse as plants, fungi, flies, nematodes, and mammals. We …

Genetic Circuits that Govern Bisexual and Unisexual Reproduction in Cryptococcus neoformans

M Feretzaki, J Heitman - PLoS genetics, 2013 - journals.plos.org
Cryptococcus neoformans is a human fungal pathogen with a defined sexual cycle. Nutrient-
limiting conditions and pheromones induce a dimorphic transition from unicellular yeast to …