Hybrid cell membrane-functionalized biomimetic nanoparticles for targeted therapy of osteosarcoma

JX Cai, JH Liu, JY Wu, YJ Li, XH Qiu… - International Journal …, 2022 - Taylor & Francis
Purpose In order to prepare a biomimetic nano-carrier which has inflammatory chemotaxis,
homologous targeting and reduce immune clearance, for targeted chemotherapy of …

Cancer cell membrane coated PLGA nanoparticles as biomimetic drug delivery system for improved cancer therapy

Y Li, J Ke, H Jia, J Ren, L Wang, Z Zhang… - Colloids and Surfaces B …, 2023 - Elsevier
Based on the immune escape and homologous adhesion ability of cancer cells, a drug
delivery system (DDS) could overcome the dilemma of immune clearance and non-specific …

Stem cell membrane vesicle–coated nanoparticles for efficient tumor‐targeted therapy of orthotopic breast cancer

W Tian, J Lu, D Jiao - Polymers for Advanced Technologies, 2019 - Wiley Online Library
Nanoparticles‐based drug delivery strategies have been widely researched for cancer
therapy. However, most of them are expected to accumulate in tumor sites via the enhanced …

Novel methotrexate prodrug-targeted drug delivery system based on PEG–lipid–PLA hybrid nanoparticles for enhanced anticancer efficacy and reduced toxicity of …

Y Li, J Lin, H Wu, M Jia, C Yuan, Y Chang… - Journal of Materials …, 2014 - pubs.rsc.org
In the present study we have investigated novel MTX prodrug-targeted and MMC-loaded
PLA–lipid–PEG hybrid NPs. These employ a double emulsion solvent evaporation method …

Platelet-tumor cell hybrid membrane-camouflaged nanoparticles for enhancing therapy efficacy in glioma

L Wu, Q Li, J Deng, J Shen, W Xu, W Yang… - International Journal …, 2021 - Taylor & Francis
Purpose Cell membrane-camouflaged nanoparticles (NPs) are drawing increasing attention
because their surfaces acquire some characteristics of the cell membranes, making them a …

Chitosan-modified PLGA nanoparticles tagged with 5TR1 aptamer for in vivo tumor-targeted drug delivery

S Taghavi, M Ramezani, M Alibolandi, K Abnous… - Cancer letters, 2017 - Elsevier
In this study, we reported epirubicin (Epi) encapsulated nanoparticles (NPs) formulated with
biocompatible and biodegradable poly (lactic-co-glycolic acid)(PLGA) modified with …

Co-delivery of doxorubicin and paclitaxel by reduction/pH dual responsive nanocarriers for osteosarcoma therapy

Y Li, H Hou, P Zhang, Z Zhang - Drug delivery, 2020 - Taylor & Francis
Nanoparticle-based drug delivery system offers a promising platform for combination cancer
therapy. However, the inefficient drug release in cells reduces the therapeutic efficacy of …

Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery

J Guo, X Gao, L Su, H Xia, G Gu, Z Pang, X Jiang… - Biomaterials, 2011 - Elsevier
Targeted delivery of therapeutic nanoparticles in a disease-specific manner represents a
potentially powerful technology especially when treating infiltrative brain tumors such as …

Dual pH-responsive multifunctional nanoparticles for targeted treatment of breast cancer by combining immunotherapy and chemotherapy

Y Liu, L Qiao, S Zhang, G Wan, B Chen, P Zhou… - Acta Biomaterialia, 2018 - Elsevier
In the present study, a dual pH-responsive multifunctional nanoparticle system was
designed for combining immunotherapy and chemotherapy to treat breast cancer through …

Dual tumor-targeted poly(lactic-co-glycolic acid)–polyethylene glycol–folic acid nanoparticles: a novel biodegradable nanocarrier for secure and efficient antitumor …

J Chen, Q Wu, L Luo, Y Wang, Y Zhong… - International journal …, 2017 - Taylor & Francis
Further specific target-ability development of biodegradable nanocarriers is extremely
important to promote their security and efficiency in antitumor drug-delivery applications. In …