Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's …

ML Selley - Neurobiology of aging, 2003 - Elsevier
Vascular risk factors increase the risk of developing Alzheimer's disease. Increased
concentrations of circulating homocysteine are associated with an increased risk of both …

Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons

ML Selley - Journal of neuroscience research, 2004 - Wiley Online Library
Increased circulating concentrations of homocysteine may be a risk factor for Alzheimer's
disease and cognitive dysfunction in normal aging. Asymmetric dimethylarginine (ADMA) is …

Reduction in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in the cerebrospinal fluid during aging and in patients with Alzheimer's …

T Abe, H Tohgi, T Murata, C Isobe, C Sato - Neuroscience letters, 2001 - Elsevier
To investigate the significance of nitric oxide (NO)-mediated neuron death in aging and
Alzheimer's disease (AD), the concentration of asymmetrical dimethylarginine (ADMA), an …

Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease

S Arlt, F Schulze, M Eichenlaub, R Maas… - Dementia and geriatric …, 2008 - karger.com
Background: Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric
oxide (NO) synthase and may alter NO production during pathological conditions …

Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease

S Arlt, E Schwedhelm, H Kölsch, H Jahn… - Journal of …, 2012 - content.iospress.com
Dimethylarginine and homocysteine metabolism are closely linked and alterations of both
were observed in plasma and cerebrospinal fluid (CSF) of patients with Alzheimer's disease …

Decreased levels of serum nitric oxide in different forms of dementia

L Corzo, R Zas, S Rodríguez, L Fernández-Novoa… - Neuroscience …, 2007 - Elsevier
Nitric oxide is involved in normal physiological functions and also in pathological processes
leading to tissue damage due, in part, to its free radical nature (oxidative stress). Oxidative …

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with …

ML Selley, DR Close, SE Stern - Neurobiology of aging, 2002 - Elsevier
There is evidence that increased blood concentrations of homocysteine may be a risk factor
for Alzheimer's disease.(E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid …

A cross-sectional study of homocysteine-, NO-levels, and CT-findings in Alzheimer dementia, vascular dementia and controls

M Folin, S Baiguera, M Gallucci, MT Conconi… - Biogerontology, 2005 - Springer
Repetitive measurement with neuroimaging techniques could be useful instruments
permitting to differentiate between Alzheimer disease (AD) and vascular dementia (VD). The …

Asymmetric dimethylarginine: a possible link between vascular disease and dementia

M Asif, R Louis Soiza, M McEvoy… - Current Alzheimer …, 2013 - ingentaconnect.com
There is good epidemiological evidence that vascular disease predisposes to cognitive
decline and dementia. The impact of vascular disease on dementia is likely to increase …

Elevated levels of plasma homocyst (e) ine and asymmetric dimethylarginine in elderly patients with stroke

JH Yoo, SC Lee - Atherosclerosis, 2001 - Elsevier
Cerebrovascular risk factors, including hypertension, smoking, diabetes mellitus, aging,
dyslipidemia, and hyperhomocyst (e) inemia are linked to endothelial dysfunction …