PURPOSE: Necrotizing enterocolitis (NEC) remains a major cause of morbidity and death in
neonates. Evidence suggests that an imbalance between activated proinflammatory …

BACKGROUND/PURPOSE: The aim of this study was to evaluate the effects of maternal
nicotine exposure during gestation on injury severity of small intestine in the newborn rats …

Necrotizing enterocolitis (NEC) is a disease of neonates that is increasing in incidence and
often results in significant morbidity and mortality. Carbon monoxide (CO), a byproduct of the …

INTRODUCTION: Hyperbaric oxygen (HBO) therapy is known to increase oxygen
concentration in tissues leading to induction of an adaptive increase in antioxidants …

The authors developed an experimental model of necrotizing enterocolitis (NEC) by hypoxia-
reoxygenation, and determined the content of malondialdehyde levels as an index of lipid …

BACKGROUND/PURPOSE: Hypoxia and ischemia appear to play an important role in the
pathogenesis of necrotizing enterocolitis (NEC), which may be related to oxygen-derived …

BACKGROUND: Oxidative stress has been implicated in the pathogenesis of necrotizing
enterocolitis (NEC). In this study, we compared the global oxidant/antioxidant status by …

Necrotizing enterocolitis (NEC) is a disease of newborns characterized by gut barrier failure.
We reasoned that upregulation of inducible nitric oxide synthase (iNOS) may result in …

Background/Purpose: The pathogenesis of necrotizing enterocolitis (NEC) is unknown.
Ischemia and reperfusion (I/R) injury has been considered a major contributing factor. Nitric …

Background Necrotizing enterocolitis (NEC) continues to be a devastating condition among
preterm infants. Nitric oxide, which is synthesized in the intestine by endothelial nitric oxide …