Protective effect of dietary flavonoid quercetin against lipemic-oxidative hepatic injury in hypercholesterolemic rats

AD Mariee, GM Abd-Allah… - Pharmaceutical …, 2012 - Taylor & Francis
Context: Quercetin, a dietary-derived flavonoid, is ubiquitous in fruits and vegetables and
plays important roles in human health by virtue of its antioxidant activity. Objective: This …

The high antioxidative power of quercetin (aglycone flavonoid) and its glycone (rutin) avert high cholesterol diet induced hepatotoxicity and inflammation in Swiss …

K Sikder, SB Kesh, N Das, K Manna, S Dey - Food & Function, 2014 - pubs.rsc.org
The present study demonstrates for the first time the protective role of two common
flavonoids, quercetin and its glycone rutin, against high cholesterol diet (2%) induced …

Cholesterol metabolism is modulated by quercetin in rats

L Zhao, J Wu, Y Wang, J Yang, J Wei… - Journal of agricultural …, 2011 - ACS Publications
Quercetin has attracted much attention recently because of its antioxidant capacity and
potential in the prevention of chronic degenerative diseases. However, its actions and the …

The flavonoid quercetin inhibits dimethylnitrosamine‐induced liver damage in rats

ES Lee, HE Lee, JY Shin, S Yoon… - Journal of pharmacy …, 2003 - Wiley Online Library
Quercetin, one of the most abundant flavonoids in human diet has been reported to exhibit a
wide range of pharmacological properties. In this study, we investigated the protective effect …

Quercetin and β-sitosterol prevent high fat diet induced dyslipidemia and hepatotoxicity in Swiss albino mice

K Sikder, N Das, SB Kesh, S Dey - 2014 - nopr.niscpr.res.in
High fat diet group showed a significant rise in serum and hepatic total cholesterol,
triglyceride and atherogenic index which are major biomarkers of dyslipidemia and …

[PDF][PDF] Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin

JF Su, CJ Guo, JY Wei, JJ Yang, YG Jiang… - Biomedical and …, 2003 - besjournal.com
Objective To investigate the possible protection provided by oral quercetin pretreatment
against hepatic ischemia-reperfusion injury in rats. Methods The quercetin (0.13 mmol/kg) …

Quercetin dihydrate and gallate supplements lower plasma and hepatic lipids and change activities of hepatic antioxidant enzymes in high cholesterol-fed rats

SH Bok, SY Park, YB Park, MK Lee… - … journal for vitamin …, 2002 - econtent.hogrefe.com
This study was designed to test the lipid-lowering and antioxidant activity of two
bioflavonoids, quercetin dihydrate and gallate. Four groups of rats were given a …

Quercetin treatment ameliorates systemic oxidative stress in cirrhotic rats

EK Vieira, S Bona, FC Di Naso… - International …, 2011 - Wiley Online Library
Our aim was to investigate whether the antioxidant quercetin protects against liver injury and
ameliorates the systemic oxidative stress in rats with common bile duct ligation. Secondary …

Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice

SM Jeong, MJ Kang, HN Choi… - Nutrition research and …, 2012 - synapse.koreamed.org
This study investigated the hypoglycemic, hypolipidemic, and antioxidant effects of dietary
quercetin in an animal model of type 2 diabetes mellitus. Four-week-old C57BL/KsJ-db/db …

Quercetin decreases high-fat diet induced body weight gain and accumulation of hepatic and circulating lipids in mice

EF Hoek-Van Den Hil, EM van Schothorst… - Genes & nutrition, 2014 - Springer
Dietary flavonoids may protect against cardiovascular diseases (CVD). Increased circulating
lipid levels and hepatic lipid accumulation are known risk factors for CVD. The aim of this …