In Africa, sickle cell disease (SCD) is a major public health problem with over 200,000
babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are …

Background Africa has the highest burden of Sickle cell disease (SCD) but there are few
large, systematic studies providing reliable descriptions of the disease spectrum. Tanzania …

Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Sickle cell anemia (SCA) is the commonest severe monogenic disorders of humans. The
disease has been highly characterized in high‐income countries but not in sub‐Saharan …

Background The first survey on sickle cell disease (SCD) done in Uganda in 1949, reported
the district of Bundibugyo in Western Uganda to have the highest sickle cell trait (SCT) …

Background. South Africa has a low incidence of sickle cell disease (SCD). However, its
demographics are changing because of immigration from sub-Saharan African countries …

Objectives: Tanzania has the third highest birth rate of sickle cell anaemia (SCA) in Africa,
but few studies describe severity of complications or available treatments, especially in …

Background/objective Sickle cell disease (SCD) is a monogenic disease with multiple
phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria …

Introduction: sickle cell disease (SCD) is a hereditary red blood cell disorder of public health
importance globally with Nigeria the epicenter zone in Africa. There is a paucity of …

Objectives Sickle cell disease (SCD) encompasses health complications, primarily affecting
the hematologic system and leading to high death rates in childhood. As a rule, the World …