Genetic influence of plasma homocysteine on Alzheimer's disease

T Roostaei, D Felsky, A Nazeri, PL De Jager… - Neurobiology of …, 2018 - Elsevier
Observational studies have consistently reported elevated plasma homocysteine as a risk
factor for Alzheimer's disease (AD). However, results from clinical trials of homocysteine …

Plasma homocysteine levels are not increased in murine models of Alzheimer's disease

D Santiard-Baron, J Aupetit, N Janel - Neuroscience research, 2005 - Elsevier
Alzheimer's disease (AD) patients tend to have increased plasma levels of homocysteine.
However, it is unclear whether abnormality in homocysteine levels is a primary cause of …

Plasma homocysteine levels and risk of Alzheimer disease

JA Luchsinger, MX Tang, S Shea, J Miller, R Green… - Neurology, 2004 - AAN Enterprises
Objective: To explore the association between high homocysteine levels and risk of
Alzheimer disease (AD) in the Washington Heights-Inwood Columbia Aging Project …

Plasma homocysteine and risk of mild cognitive impairment

C Reitz, MX Tang, J Miller, R Green… - Dementia and geriatric …, 2009 - karger.com
Abstract Background and Objective: There are conflicting data relating homocysteine levels
to the risk of Alzheimer's disease (AD). We sought to explore whether fasting plasma …

Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?

S Seshadri - Journal of Alzheimer's Disease, 2006 - content.iospress.com
Elevated plasma homocysteine (tHcy) concentrations have been associated with an
increased risk of developing dementia and Alzheimer's disease (AD). It is not clear …

The association between homocysteine and memory in older adults

ME Nelson, R Andel, Z Nedelska… - Journal of …, 2021 - content.iospress.com
Background: Identifying modifiable risk factors for cognitive decline can reduce burden of
dementia. Objective: We examined whether homocysteine was associated with memory …

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

B Hooshmand, T Polvikoski, M Kivipelto, M Tanskanen… - Brain, 2013 - academic.oup.com
Elevated plasma total homocysteine is associated with increased risk of
dementia/Alzheimer's disease, but underlying pathophysiological mechanisms are not fully …

Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?

JM Zhuo, H Wang, D Praticò - Trends in pharmacological sciences, 2011 - cell.com
Alzheimer's disease (AD) is the most common form of neurodegenerative disease. The vast
majority cases of AD are sporadic, without clear cause, and a combination of environmental …

Homocysteine and cerebral atrophy: the epidemiology of dementia in Singapore study

B Tan, N Venketasubramanian… - Journal of …, 2018 - content.iospress.com
Background: Plasma homocysteine levels are increasingly studied as a potential risk factor
for dementia. Elevated homocysteine levels have been linked with gray and white matter …

Homocysteine as a predictor of cognitive decline in Alzheimer's disease

A Oulhaj, H Refsum, H Beaumont… - … journal of geriatric …, 2010 - Wiley Online Library
Objective Moderately elevated levels of plasma total homocysteine are associated with an
increased risk of developing Alzheimer's disease. We have tested whether baseline …