The Effect of Class II Major Histocompatibility Complex Expression on Adherence of Helicobacter pylori and Induction of Apoptosis in Gastric Epithelial Cells: A …
X Fan, SE Crowe, S Behar, H Gunasena, G Ye… - The Journal of …, 1998 - rupress.org
Helicobacter pylori infection is associated with gastric epithelial damage, including
apoptosis, ulceration, and cancer. Although bacterial factors and the host response are …
apoptosis, ulceration, and cancer. Although bacterial factors and the host response are …
Helicobacter pylori Infection in Immunized Mice Lacking Major Histocompatibility Complex Class I and Class II Functions
J Pappo, D Torrey, L Castriotta, A Savinainen… - Infection and …, 1999 - Am Soc Microbiol
The role of major histocompatibility complex (MHC) class I-and class II-restricted functions in
Helicobacter pylori infection and immunity upon oral immunization was examined in vivo …
Helicobacter pylori infection and immunity upon oral immunization was examined in vivo …
Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis
X Fan, H Gunasena, Z Cheng, R Espejo… - The journal of …, 2000 - journals.aai.org
Infection by Helicobacter pylori leads to injury of the gastric epithelium and a cellular
infiltrate that includes CD4+ T cells. H. pylori binds to class II MHC molecules on gastric …
infiltrate that includes CD4+ T cells. H. pylori binds to class II MHC molecules on gastric …
Vaccine-Induced Reduction of Helicobacter pylori Colonization in Mice Is Interleukin-12 Dependent but Gamma Interferon and Inducible Nitric Oxide Synthase …
CA Garhart, FP Heinzel, SJ Czinn… - Infection and …, 2003 - Am Soc Microbiol
Previous studies with mice have shown that major histocompatibility complex class II (MHC-
II) is required for protection from Helicobacter pylori, while MHC-I and antibodies are not …
II) is required for protection from Helicobacter pylori, while MHC-I and antibodies are not …
Helicobacter pylori-specific antibodies impair the development of gastritis, facilitate bacterial colonization, and counteract resistance against infection
AA Akhiani, K Schön, LE Franzén… - The Journal of …, 2004 - journals.aai.org
In recent years, Abs have been considered a correlate rather than an effector of resistance
against Helicobacter pylori infection. However, it is still poorly understood to what extent Ab …
against Helicobacter pylori infection. However, it is still poorly understood to what extent Ab …
Gastric Mucosal Recognition of Helicobacter pylori Is Independent of Toll-Like Receptor 4
F Bäckhed, B Rokbi, E Torstensson… - The Journal of …, 2003 - academic.oup.com
Little is known about the interactions between Helicobacter pylori which specializes in
colonizing the mucin layer that covers the gastric mucosa, and primary gastric epithelial …
colonizing the mucin layer that covers the gastric mucosa, and primary gastric epithelial …
Helicobacter pylori Modulates Lymphoepithelial Cell Interactions Leading to Epithelial Cell Damage through Fas/Fas Ligand Interactions
J Wang, X Fan, C Lindholm, M Bennett… - Infection and …, 2000 - Am Soc Microbiol
Helicobacter pylori causes a common chronic infection of humans that leads to epithelial cell
damage. Studies have shown that apoptosis of the gastric epithelium is increased during …
damage. Studies have shown that apoptosis of the gastric epithelium is increased during …
Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice
LE Smythies, KB Waites, JR Lindsey… - The Journal of …, 2000 - journals.aai.org
To elucidate the pathogenesis of Helicobacter pylori-associated gastritis, we studied
immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-γ−/− and IL …
immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-γ−/− and IL …
Expression of HLA-DR, costimulatory molecules B7-1, B7-2, intercellular adhesion molecule-1 (ICAM-1) and Fas ligand (FasL) on gastric epithelial cells in Helicobacter pylori …
A Archimandritis, S Sougioultzis… - Clinical & …, 2000 - academic.oup.com
There is evidence that Helicobacter pylori infection up-regulates the expression of HLA class
II molecules by gastric epithelial cells (GEC). In this study we evaluated whether GEC are …
II molecules by gastric epithelial cells (GEC). In this study we evaluated whether GEC are …
Characterization of the Helicobacter pylori Cysteine-Rich Protein A as a T-Helper Cell Type 1 Polarizing Agent
L Deml, M Aigner, J Decker, A Eckhardt… - Infection and …, 2005 - Am Soc Microbiol
ABSTRACT Predominant T-helper 1 (Th1) responses with increased gamma interferon (IFN-
γ) levels have been proposed to play an important role in Helicobacter pylori-induced …
γ) levels have been proposed to play an important role in Helicobacter pylori-induced …