Objective: To determine if individuals ultimately diagnosed with Alzheimer disease (AD)
exhibited evidence of cognitive impairment on neuropsychological tests administered …

We review the literature on cognitive functioning during the transition from normal aging to
clinical Alzheimer's disease (AD). There is ample empirical evidence that deficits across …

Objective To characterize the course of cognitive decline during the prodromal phase of
Alzheimer disease. Design Longitudinal cohort study with up to 16 years of observation …

Objectives To examine the ability of the total score and individual items from the Mini-Mental
State Examination in predicting the development of Alzheimer disease (AD) across a 3-and …

Objective: To determine whether clinically nondemented elderly individuals with
pathologically confirmed preclinical AD are characterized by cognitive decline as measured …

Objective: To determine whether neuropsychological tests accurately predict incident
Alzheimer disease (AD) after 5 and 10 years in participants of the Canadian Study of Health …

Background To understand the earliest signs of cognitive decline caused by Alzheimer
disease (AD) and other illnesses causing dementia, information is needed from well …

Better knowledge of the preclinical phase of Alzheimer's disease would be an important
advance to allow earlier treatment of this ominous disease. This prodromal period was …

To determine the size of the impairment across different cognitive domains in preclinical
Alzheimer's disease (AD), a meta-analysis based on 47 studies involving 9,097 controls and …

Although neuropathologic studies showed that early-onset Alzheimer's disease (EAD) and
“senile dementia” were indistinguishable, clinical studies suggested that EAD and late-onset …