Evaluating retinal toxicity of a new heavy intraocular dye, using a model of perfused and isolated retinal cultures of bovine and human origin

K Januschowski, S Mueller, MS Spitzer… - Graefe's Archive for …, 2012 - Springer
Background Dyes such as brilliant blue (BBG) are used during vitreoretinal surgery to
visualize anatomical structures. By adding deuterium oxide (D2O), surgeons have tried to …

Investigating the biocompatibility of two new heavy intraocular dyes for vitreoretinal surgery with an isolated perfused vertebrate retina organ culture model and a …

K Januschowski, S Mueller, MS Spitzer… - Graefe's Archive for …, 2012 - Springer
Background During vitreoretinal surgery, vital dyes are used to visualize anatomical
structures. Substances with a density higher than water are added to facilitate sedimentation …

The effects of the intraocular dye brilliant blue G (BBG) mixed with varying concentrations of glucose on retinal function in an isolated perfused vertebrate retina

K Januschowski, S Mueller, MS Spitzer… - Graefe's Archive for …, 2011 - Springer
Background During vitreoretinal surgery, vital dyes such as brilliant blue G (BBG) are used
to visualize anatomical structures. By adding glucose to a concentration of 5%, many …

Intravital staining of the internal limiting membrane with a novel heavy solution of brilliant blue G

H Gerding, M Timmermann… - Klinische Monatsblätter für …, 2011 - thieme-connect.com
Hintergrund: Es war Ziel des Projektes hydrodynamische Eigenschaften und klinische
Effizienz einer neuen, schweren Farbstoffzubereitung von Brilliant Blau G (BBG, 0, 25 …

Trityl dyes patent blue V and brilliant blue G–clinical relevance and in vitro analysis of the function of the outer blood-retinal barrier

S Mennel, CH Meyer, JC Schmidt, S Kaempf… - Vital Dyes in …, 2008 - karger.com
The use of vital dyes during vitrectomy allows easier removal of less recognizable structures
like epiretinal membranes or the internal limiting membrane (ILM). In recent years …

The retinal biocompatibility of dyes in the ex vivo model of the isolated superfused vertebrate retina

M Lüke, S Grisanti, J Lüke… - …, 2013 - karger.com
Background: Peeling of the internal limiting membrane or epiretinal membranes is a
successful principle in macular surgery to achieve a functional benefit. Different dyes are …

Electrophysiological effects of Brilliant Blue G in the model of the isolated perfused vertebrate retina

M Lüke, K Januschowski, J Beutel, C Lüke… - Graefe's Archive for …, 2008 - Springer
Background To facilitate epiretinal or inner limiting membrane peeling dyes like Indocyanine
Green (ICG) as well as Trypan Blue (TB) were used so far. However, toxic effects on the …

[HTML][HTML] Retinal biocompatibility of brilliant blue g with deuterated water for chromovitrectomy

E Badaró, M Moraes-Filho, M Maia… - Journal of Ophthalmic …, 2014 - ncbi.nlm.nih.gov
Purpose To investigate the retinal biocompatibility of Brilliant Blue G with deuterated water
(BBG-D2O) as a vital dye for chromovitrectomy. Methods In this animal study, 0.05 mL of …

Administration of novel dyes for intraocular surgery: an in vivo toxicity animal study

F Schuettauf, C Haritoglou, CA May… - … & visual science, 2006 - iovs.arvojournals.org
purpose. To investigate the effect of intravitreal injections of new vital dyes on the retina, the
retinal pigment epithelium (RPE) and the choroid in an in vivo rat model. methods. Rats …

New dual dye for vitreoretinal surgery with increased transparency

A Mohr, P Cendoya, J Wilinska, M Apostu… - BMJ Open …, 2022 - bmjophth.bmj.com
Objectives To develop a new dye formulation for vitreoretinal surgery, which shows
increased transparency for better intraoperative handling with better parameters important …