In Eukaryotes, DNA is wound around the histone octamer forming the basic chromatin unit,
the nucleosome. Atomic structures have been obtained from crystallography and single …

Genomic DNA in eukaryotes is organized into chromatin through association with core
histone proteins to form nucleosomes. To understand the structure and function of …

A long strand of DNA is wrapped around the core histone and forms a nucleosome.
Although the nucleosome has long been assumed to be folded into 30-nm chromatin fibres …

The high-resolution structure of a nucleosome core particle gives us our first detailed look at
the primary level of eukaryotic DNA organization. The structure reveals the nature of histone …

Twenty-five years have passed since the appearance of the first atomistic model of the
nucleosome structure, and since then the number of new structures has gradually increased …

The compaction level of arrays of nucleosomes may be understood in terms of the balance
between the self-repulsion of DNA (principally linker DNA) and countering factors including …

Nuclear processes depend on the organization of chromatin, whose basic units are cylinder-
shaped complexes called nucleosomes. A subset of mammalian nucleosomes in situ (inside …

The basic unit of chromatin, the nucleosome core particle (NCP), controls how DNA in
eukaryotic cells is compacted, replicated and read. Since its discovery, biochemists have …

We have characterized the structure of transcriptionally active nucleosome subunits using
electron spectroscopic imaging. Individual nucleosomes were analyzed in terms of total …

Among the multiple effects involved in chromatin condensation and decondensation
processes, interactions between nucleosome core particles are suspected to play a crucial …