Effects of quercetin on liver damage in rats with carbon tetrachloride-induced cirrhosis

A Pavanato, MJ Tuñón, S Sánchez-Campos… - Digestive diseases and …, 2003 - Springer
Flavonoids are reported to exhibit a wide variety of biological effects, including antioxidant
and free radical-scavenging activities. Evidence of oxidative reactions is often associated …

Effect of antioxidant treatment on fibrogenesis in rats with carbon tetrachloride‐induced cirrhosis

S Bona, LI Filippin, FC Di Naso… - International …, 2012 - Wiley Online Library
Aim. This study aimed to assess the antioxidant activity of quercetin (Q) in an experimental
model of cirrhosis induced by CCl4 inhalation. Materials and Methods. We used 25 male …

Quercetin prevents oxidative stress in cirrhotic rats

PM Amália, MN Possa, MC Augusto… - Digestive diseases and …, 2007 - Springer
Our aim was to study the protective effect of quercitin on liver cirrhosis induced by carbon
tetrachloride (CCl 4) in rats and its relationship with liver morphology. Thirty male Wistar rats …

The flavonoid quercetin ameliorates liver damage in rats with biliary obstruction

W Peres, MJ Tuñón, PS Collado, S Herrmann… - Journal of …, 2000 - Elsevier
Background/Aims: Our aim was to investigate whether the antioxidant quercetin might
protect against liver injury in chronically biliary obstructed rats. Methods: Secondary biliary …

Quercetin treatment ameliorates systemic oxidative stress in cirrhotic rats

EK Vieira, S Bona, FC Di Naso… - International …, 2011 - Wiley Online Library
Our aim was to investigate whether the antioxidant quercetin protects against liver injury and
ameliorates the systemic oxidative stress in rats with common bile duct ligation. Secondary …

Quercetin reverses experimental cirrhosis by immunomodulation of the proinflammatory and profibrotic processes

S Casas‐Grajales, LF Vázquez‐Flores… - Fundamental & …, 2017 - Wiley Online Library
The ability of quercetin to reverse an established cirrhosis has not yet been investigated.
Therefore, the aim of this study was to examine the efficacy of this flavonoid in reversing …

The flavonoid quercetin inhibits dimethylnitrosamine‐induced liver damage in rats

ES Lee, HE Lee, JY Shin, S Yoon… - Journal of pharmacy …, 2003 - Wiley Online Library
Quercetin, one of the most abundant flavonoids in human diet has been reported to exhibit a
wide range of pharmacological properties. In this study, we investigated the protective effect …

Protective effects of quercetin and quercetin-5', 8-disulfonate against carbon tetrachloride-caused oxidative liver injury in mice

Y Cui, Y Han, X Yang, Y Sun, Y Zhao - Molecules, 2013 - mdpi.com
Oxidative stress is one of the major factors in the pathogenesis of liver disease. Quercetin is
a plant-based antioxidant traditionally used as a treatment for hepatic injury, but its poor …

Inhibitory effects of quercetin on the progression of liver fibrosis through the regulation of NF-кB/IкBα, p38 MAPK, and Bcl-2/Bax signaling

R Wang, H Zhang, Y Wang, F Song, Y Yuan - International …, 2017 - Elsevier
Quercetin, a natural flavonoid, has been used as a nutritional supplement for its anti-
inflammatory and antioxidative properties. Quercetin was reported to exhibit a wide range of …

Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis

YO Teselkin, IV Babenkova, VK Kolhir… - Phytotherapy …, 2000 - Wiley Online Library
The antioxidant effect of dihydroquercetin (DHQ) was studied in Wistar rats with
experimental hepatitis, caused by tetrachloromethane (CCl4). Animals were divided into …