Elevated plasma homocysteine (tHcy) concentrations have been associated with an
increased risk of developing dementia and Alzheimer's disease (AD). It is not clear …

Objective: Several studies have shown that plasma total homocysteine (tHcy) concentration
is elevated in Alzheimer's disease (AD). However, it is not clear whether elevated plasma …

Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

Objective Moderately elevated levels of plasma total homocysteine are associated with an
increased risk of developing Alzheimer's disease. We have tested whether baseline …

Abstract Background and Objective: There are conflicting data relating homocysteine levels
to the risk of Alzheimer's disease (AD). We sought to explore whether fasting plasma …

There is some evidence from recent observational studies that hyperhomocysteinemia is a
risk factor for cognitive dysfunction, including Alzheimer's disease and vascular dementia …

Identification of modifiable risk factors provides a crucial approach to the prevention of
dementia. Nutritional or nutrient-dependent risk factors are especially important because …

BACKGROUND: Prospective cohort studies have not been consistent in showing an
association between serum homocysteine and dementia. OBJECTIVE: To conduct a meta …

Background In cross-sectional studies, elevated plasma homocysteine levels have been
associated with poor cognition and dementia. Studies of newly diagnosed dementia are …

A hypothesis is proposed that reconciles the epidemiological observation of elevated
homocysteine in Alzheimer's disease (AD) with clinical features of the disease, particularly …