Mechanisms underlying normal fracture healing and risk factors for delayed healing

C Cheng, D Shoback - Current Osteoporosis Reports, 2019 - Springer
Abstract Purpose of Review Substantial advances have been made in understanding the
biological basis of fracture healing. Yet, it is unclear whether the presence of osteoporosis or …

The biology of fracture healing in osteoporosis and in the presence of anti-osteoporotic drugs

DJ Hak - Injury, 2018 - Elsevier
Compromised bone strength in osteoporosis predisposes patients to an increased fracture
risk. The management of these fractures is complicated due to the poor bone quality, which …

(iv) Osteoporosis treatments and their effect on fracture healing

SE Johnson-Lynn, R Francis, A McCaskie - Current Orthopaedics, 2008 - Elsevier
Osteoporosis causes an increased risk of fracture through decreased bone mineral density,
disruption of bone microarchitecture and reduction in non-collagenous proteins. The effect of …

Fracture healing in osteoporotic fractures: Is it really different?: A basic science perspective

P Giannoudis, C Tzioupis, T Almalki, R Buckley - Injury, 2007 - Elsevier
Osteoporosis is a major health problem characterized by compromised bone strength that
predisposes patients to an increased risk of fracture. Osteoporotic patients differ from normal …

[HTML][HTML] The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies

EA Gorter, CR Reinders, P Krijnen… - Bone reports, 2021 - Elsevier
Introduction Osteoporosis is characterised by low bone mass and micro-architectural
deterioration of bone structure. Its treatment is directed at the processes of bone formation or …

Fracture repair: general aspects and influence of osteoporosis and anti-osteoporosis treatment

JM Féron, R Mauprivez - Injury, 2016 - Elsevier
Bone differs from other tissues in its capacity to self-repair after a fracture. The low bone
mass and structural deterioration of bone associated with osteoporosis increases the risk of …

Effect of osteoporosis medications on fracture healing

V Hegde, JE Jo, P Andreopoulou, JM Lane - Osteoporosis International, 2016 - Springer
Antiosteoporotic medications are often used to concurrently treat a patient's fragility fractures
and underlying osteoporosis. This review evaluates the existing literature from animal and …

[HTML][HTML] Fracture healing and drug therapies in osteoporosis

A Hoang-Kim, L Gelsomini, D Luciani… - Clinical Cases in …, 2009 - ncbi.nlm.nih.gov
Fracture repair has not been fully optimised and there is opportunity to increase the healing
rate and reduce the number of complications using pharmacological means. While most anti …

Fracture healing in a rat osteopenia model.

WR Walsh, P Sherman, CR Howlett… - … Research (1976-2007 …, 1997 - journals.lww.com
Fracture healing is influenced by mechanical and biologic factors. The capacity for fracture
repair has been reported to decrease with age, although the risk of fracture increases with …

Animal models for fracture treatment in osteoporosis

M Egermann, J Goldhahn, E Schneider - Osteoporosis international, 2005 - Springer
Demographic changes in the age structure of occidental populations are giving rise to
osteoporosis and associated fractures, which are becoming a major public health burden …