Synthesis of novel psoralen analogues and their in vitro antitumor activity

CS Francisco, LR Rodrigues, NM Cerqueira… - Bioorganic & medicinal …, 2013 - Elsevier
New tetracyclic benzofurocoumarin (benzopsoralen) analogues were synthesized and their
inhibitory effect on the growth of tumor cell lines was evaluated. The human tumor cell lines …

Novel benzopsoralen analogues: synthesis, biological activity and molecular docking studies

CS Francisco, LR Rodrigues, NM Cerqueira… - European journal of …, 2014 - Elsevier
New benzopsoralen analogues were synthesized and their inhibitory effect on the growth of
tumourtumour cell lines (MDA MB231 and TCC-SUP) was evaluated. The in vitro antitumour …

Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies

AMAG Oliveira, MMM Raposo… - European journal of …, 2006 - Elsevier
Eight psoralens have been evaluated for their ability to inhibit the in vitro growth of three
human tumor cell lines representing different tumor types, MCF-7 (breast cancer), NCI-H460 …

Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines

CS Francisco, LR Rodrigues, NM Cerqueira… - European journal of …, 2012 - Elsevier
The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is
described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB …

Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4

EC Row, SA Brown, AV Stachulski… - Bioorganic & medicinal …, 2006 - Elsevier
Furanocoumarins have been shown to inhibit CYP3A4 in vitro with varying degrees of
potency [Pharmacogenetics1997, 7, 391–396; Chem. Res. Toxicol. 1998, 11, 252–259; …

Synthesis and antitumor evaluation of benzopsoralen analogues

AMAG Oliveira, AMF Oliveira‐Campos… - Chemistry & …, 2007 - Wiley Online Library
The synthesis of five new tetracyclic benzopsoralen analogues, compounds 2–6, with 9H‐
xanthen‐9‐one or 9H‐carbazole frameworks, is described. Their inhibitory effects on the …

Synthesis, cytotoxicity and in silico study of some novel benzocoumarin-chalcone-bearing aryl ester derivatives and benzocoumarin-derived arylamide analogs

NA Abdul-Ridha, AD Salmaan, R Sabah… - … für Naturforschung B, 2021 - degruyter.com
The development of new prostate cancer protein receptor cytochrome P450 17A1 inhibitors
offers the possibility of generating structures of increased potency. To this end, the chalcone …

Structure and biological activity of furocoumarins

R Gambari, I Lampronti, N Bianchi, C Zuccato… - Bioactive Heterocycles …, 2007 - Springer
In this review we summarize the structure and biological effects of linear and angular
psoralens. These compounds exhibit very interesting biological effects on cell cycle …

Synthesis of some new benzoxazole derivatives and investigation of their anticancer activities

D Osmaniye, BK Çelikateş, BN Sağlık, S Levent… - European Journal of …, 2021 - Elsevier
Phortress is an anticancer prodrug, which has active metabolite (5F-203) being potent
agonist of the aryl hydrocarbon receptor (AhR). The 5F-203 switches on cytochrome P450 …

Synthesis of Furo[3,2‐g][1,4]Benzoxazin‐3‐ones, New Psoralen Isosters

A Chilin, A Confente, G Pastorini… - European Journal of …, 2002 - Wiley Online Library
Abstract Furobenzoxazin‐3‐one, a new tricyclic nucleus, was synthesised in two different
and straightforward routes: the first route consisted of condensing a furan ring onto a …