New benzopsoralen analogues were synthesized and their inhibitory effect on the growth of tumourtumour cell lines (MDA MB231 and TCC-SUP) was evaluated. The in vitro antitumour …
AMAG Oliveira, MMM Raposo… - European journal of …, 2006 - Elsevier
Eight psoralens have been evaluated for their ability to inhibit the in vitro growth of three human tumor cell lines representing different tumor types, MCF-7 (breast cancer), NCI-H460 …
The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB …
EC Row, SA Brown, AV Stachulski… - Bioorganic & medicinal …, 2006 - Elsevier
Furanocoumarins have been shown to inhibit CYP3A4 in vitro with varying degrees of potency [Pharmacogenetics1997, 7, 391–396; Chem. Res. Toxicol. 1998, 11, 252–259; …
The synthesis of five new tetracyclic benzopsoralen analogues, compounds 2–6, with 9H‐ xanthen‐9‐one or 9H‐carbazole frameworks, is described. Their inhibitory effects on the …
NA Abdul-Ridha, AD Salmaan, R Sabah… - … für Naturforschung B, 2021 - degruyter.com
The development of new prostate cancer protein receptor cytochrome P450 17A1 inhibitors offers the possibility of generating structures of increased potency. To this end, the chalcone …
In this review we summarize the structure and biological effects of linear and angular psoralens. These compounds exhibit very interesting biological effects on cell cycle …
Phortress is an anticancer prodrug, which has active metabolite (5F-203) being potent agonist of the aryl hydrocarbon receptor (AhR). The 5F-203 switches on cytochrome P450 …
A Chilin, A Confente, G Pastorini… - European Journal of …, 2002 - Wiley Online Library
Abstract Furobenzoxazin‐3‐one, a new tricyclic nucleus, was synthesised in two different and straightforward routes: the first route consisted of condensing a furan ring onto a …