Vibrio cholerae strain VB1 secretes a number of enzymes into the outside medium that
utilize ATP as a substrate. Such enzymes are found in the outside medium during the mid …

Vibrio cholerae O1 organisms belonging to different biotypes and serotypes were shown to
express major outer membrane proteins (MOMPs) with subunit molecular masses of 48 to …

The bacterial protein toxin of Vibrio cholerae, cholera toxin, is a major agent involved in
severe diarrhoeal disease. Cholera toxin is a member of the AB toxin family and is …

Many strains of Vibrio cholerae non-O1 and O1 El Tor that cause diarrhea do not harbor
genes for a known secretogenic toxin. However, these strains usually elaborate a pore …

This chapter outlines present knowledge on the immune mechanisms operating against
cholera based on studies of experimental animals infected with Vibrio cholerae as well as of …

We describe here a new animal model that offers the prospect of using conventional adult
mice for direct evaluation of the protective potential of new cholera vaccines. Pretreatment of …

Parenteral cholera vaccines have for some years been removed from the WHO
recommendations. With a greater understanding of the immunology of gut infections has …

BACKGROUND OF THE INVENTION This invention relates to modified strains of Vibrio
cholerae that are useful, for example, for immunological protection against cholera and other …

Vibrio cholerae induces either non-inflammatory diarrhea or inflammatory gastroenteritis,
depending on the presence of cholera toxin, a fluid secretion inducer and a modulator of …

Mutants of Vibrio cholerae defective in intestinal colonization have been constructed.
Characterization of these mutants has led to the identification of a gene cluster involved in …