Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow–derived cells

OM Tepper, JM Capla, RD Galiano, DJ Ceradini… - Blood, 2005 - ashpublications.org
Ischemia is a known stimulus for vascular growth. Bone marrow (BM)–derived endothelial
progenitor cells (EPCs) are believed to contribute to new blood vessel growth, but the …

Time-course analysis on the differentiation of bone marrow-derived progenitor cells into smooth muscle cells during neointima formation

JM Daniel, W Bielenberg, P Stieger… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—Bone marrow-derived progenitor cells have been implicated to contribute to
neointima formation, but the time course and extent of their accumulation and differentiation …

Bone marrow-derived cells do not incorporate into the adult growing vasculature

T Ziegelhoeffer, B Fernandez, S Kostin, M Heil… - Circulation …, 2004 - Am Heart Assoc
Bone marrow-Derived cells have been proposed to form new vessels or at least incorporate
into growing vessels in adult organisms under certain physiological and pathological …

Biologic properties of endothelial progenitor cells and their potential for cell therapy

PP Young, DE Vaughan, AK Hatzopoulos - Progress in cardiovascular …, 2007 - Elsevier
Recent studies indicate that portions of ischemic and tumor neovasculature are derived by
neovasculogenesis, whereby bone marrow (BM)–derived circulating endothelial progenitor …

Augmentation of postnatal neovascularization with autologous bone marrow transplantation

S Shintani, T Murohara, H Ikeda, T Ueno, K Sasaki… - Circulation, 2001 - Am Heart Assoc
Background—Endothelial progenitor cells (EPCs) have been identified in adult human
peripheral blood. Because circulating EPCs should originate from bone marrow (BM), we …

[HTML][HTML] The bone marrow-derived endothelial progenitor cell response is impaired in delayed wound healing from ischemia

SM Bauer, LJ Goldstein, RJ Bauer, H Chen… - Journal of vascular …, 2006 - Elsevier
OBJECTIVE: Vasculogenesis relies on the recruitment of bone marrow-derived endothelial
progenitor cells (BMD EPCs) and is stimulated by tissue-level ischemia. We hypothesized …

The emerging role of the bone marrow-derived stem cells in (therapeutic) angiogenesis

P Carmeliet, A Luttun - Thrombosis and haemostasis, 2001 - thieme-connect.com
Proper formation of blood vessels (angiogenesis) is essential for development, reproduction
and wound healing. When derailed, angiogenesis contributes to numerous lifethreatening …

Mobilization of bone marrow–derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cells

TJ O'Neill IV, BR Wamhoff, GK Owens… - Circulation …, 2005 - Am Heart Assoc
Bone marrow–derived cells (BMCs) have been implicated as a modifiers of vascular growth
either directly by transdifferentiation into endothelial cells (ECs) or indirectly through growth …

Role of endothelial progenitor cells during ischemia-induced vasculogenesis and collateral formation

J Tongers, JG Roncalli, DW Losordo - Microvascular research, 2010 - Elsevier
Cell-based therapy has emerged as a promising therapeutic tool for treatment of ischemic
cardiovascular disease. Both unselected bone marrow-derived mononuclear cells (BMNCs) …

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

I Rajantie, M Ilmonen, A Alminaite, U Ozerdem… - Blood, 2004 - ashpublications.org
Bone marrow (BM)-derived cells are thought to participate in the growth of blood vessels
during postnatal vascular regeneration and tumor growth, a process previously attributed to …