Neural synchrony in brain circuits is the mainstay of cognition, including memory processes.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that disrupts neural …

The olfactory dysfunction can signal and act as a potential biomarker of preclinical AD.
However, the precise regulatory mechanism of olfactory function on the neural pathogenesis …

Olfactory impairment is associated with prodromal Alzheimer's disease (AD) and is a risk
factor for the development of dementia. AD pathology is known to disrupt brain regions …

Alzheimer's disease (AD) is a progressive, neurodegenerative disease characterized by cell
and synapse losses and the ensued network disconnections. Olfactory impairment is …

Abstract Background Hyposmia in Alzheimer's disease (AD) is a typical early symptom
according to numerous previous clinical studies. Although amyloid-β (Aβ), which is one of …

The unique vulnerability of the olfactory system to Alzheimer's disease (AD) provides a
quintessential translational tool for understanding mechanisms of synaptic dysfunction and …

Cognitive functions such as working memory require integrated activity among different
brain regions. Notably, entorhinal cortex (EC) activity is associated with the successful …

Background Deep brain stimulation (DBS) has demonstrated potential in mitigating
Alzheimer's disease (AD). However, the invasive nature of DBS presents challenges for its …

Hyposmia is common in Alzheimer's dementia (AD) and Parkinson's disease dementia
(PDD). We evaluated the pattern of olfactory functional connectivity (FC) in AD and PDD to …

Background Olfactory dysfunction is known to be an early manifestation of Alzheimer's
disease (AD). However, the underlying mechanism, particularly the specific molecular …