Relation of plasma homocysteine to plasma amyloid beta levels

JA Luchsinger, MX Tang, J Miller, R Green… - Neurochemical …, 2007 - Springer
Background Elevated plasma homocysteine and amyloid β (Aβ) have been associated with
Alzheimer's disease (AD). We investigated the cross-sectional association between these …

Plasma homocysteine levels and risk of Alzheimer disease

JA Luchsinger, MX Tang, S Shea, J Miller, R Green… - Neurology, 2004 - AAN Enterprises
Objective: To explore the association between high homocysteine levels and risk of
Alzheimer disease (AD) in the Washington Heights-Inwood Columbia Aging Project …

[PDF][PDF] Plasma homocysteine: a new risk factor for Alzheimer's disease?

EH Mizrahi, DW Jacobsen, RP Friedland - IMAJ-RAMAT GAN-, 2002 - academia.edu
Dementia is a common and devastating public health problem, affecting an estimated
5±10% of individuals over the age of 65 [1]. Two pathologically distinct subtypes of …

Plasma homocysteine and risk of mild cognitive impairment

C Reitz, MX Tang, J Miller, R Green… - Dementia and geriatric …, 2009 - karger.com
Abstract Background and Objective: There are conflicting data relating homocysteine levels
to the risk of Alzheimer's disease (AD). We sought to explore whether fasting plasma …

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

S Seshadri, A Beiser, J Selhub… - New England journal …, 2002 - Mass Medical Soc
Background In cross-sectional studies, elevated plasma homocysteine levels have been
associated with poor cognition and dementia. Studies of newly diagnosed dementia are …

Genetic influence of plasma homocysteine on Alzheimer's disease

T Roostaei, D Felsky, A Nazeri, PL De Jager… - Neurobiology of …, 2018 - Elsevier
Observational studies have consistently reported elevated plasma homocysteine as a risk
factor for Alzheimer's disease (AD). However, results from clinical trials of homocysteine …

Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants

DS Wald, A Kasturiratne, M Simmonds - Alzheimer's & Dementia, 2011 - Elsevier
BACKGROUND: Prospective cohort studies have not been consistent in showing an
association between serum homocysteine and dementia. OBJECTIVE: To conduct a meta …

Homocysteine as a predictor of cognitive decline in Alzheimer's disease

A Oulhaj, H Refsum, H Beaumont… - … journal of geriatric …, 2010 - Wiley Online Library
Objective Moderately elevated levels of plasma total homocysteine are associated with an
increased risk of developing Alzheimer's disease. We have tested whether baseline …

Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease

J Popp, P Lewczuk, M Linnebank… - Journal of …, 2009 - content.iospress.com
Disturbed homocysteine metabolism is a risk factor for Alzheimer's disease (AD) and may
contribute to the disease pathophysiology by increasing both amyloid-β (Aβ) production and …

S-Adenosylmethionine Is Decreased in the Cerebrospinal Fluid of Patients with Alzheimer's Disease

M Linnebank, J Popp, Y Smulders, D Smith… - Neurodegenerative …, 2010 - karger.com
Background: Increased plasma homocysteine levels have been described as an
independent risk factor for Alzheimer's disease (AD), but the underlying pathophysiology is …