Research evaluation and diagnosis of probable Alzheimer's disease over the last two decades: I

OL Lopez, JT Becker, W Klunk, J Saxton, RL Hamilton… - Neurology, 2000 - AAN Enterprises
Objective: To describe the experience of a research clinic diagnosing AD during the last two
decades, with special emphasis on patients who meet the National Institute of Neurological …

Clinically diagnosed Alzheimer disease: neuropathologic findings in 650 cases

MF Mendez, AR Mastri, JH Sung… - Alzheimer Disease & …, 1992 - journals.lww.com
Despite the introduction of formal clinical criteria for Alzheimer disease (AD), the clinical
diagnosis of AD remains one of exclusion of other dementias. To determine the accuracy of …

The NINCDS‐ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: A clinicopathologic study of 57 cases

MC Tierney, RH Fisher, AJ Lewis, ML Zorzitto… - Neurology, 1988 - AAN Enterprises
Neuropathologic confirmation is required to validate the NINCDS-ADRDA Work Group
criteria for the clinical diagnosis of Alzheimer's disease (AD). Neuropathologic inclusion and …

Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology

DX Rasmusson, J Brandt, C Steele… - Alzheimer Disease & …, 1996 - journals.lww.com
Neuropathological examination confirmed the clinical diagnosis of possible or probable
Alzheimer disease (AD) in 90 of the first 100 patients who came to autopsy at the Johns …

Validation of clinical diagnostic criteria for Alzheimer's disease

JC Morris, DW McKeel Jr, K Fulling… - Annals of Neurology …, 1988 - Wiley Online Library
Clinical investigations of Alzheimer's disease (AD) have been limited by diagnostic
inaccuracy. We employed explicit clinical inclusion and exclusion criteria to identify subjects …

Clinical and research diagnostic criteria for Alzheimer's disease

M Sarazin, LC de Souza… - Neuroimaging …, 2012 - neuroimaging.theclinics.com
For more than 25 years, the diagnosis of Alzheimer's disease (AD) has been based on the
National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) and …

Comparison of pathological diagnostic criteria for Alzheimer disease

ZS Nagy, MM Esir, C Joachim, KA Jobst… - Alzheimer Disease & …, 1998 - journals.lww.com
Because the clinical picture of Alzheimer disease (AD) is often difficult to discriminate from
other dementing illnesses, the diagnosis of AD requires neuropathological confirmation …

The neuropathology of probable Alzheimer disease and mild cognitive impairment

JA Schneider, Z Arvanitakis… - Annals of Neurology …, 2009 - Wiley Online Library
Objective Mixed pathologies are common in older persons with dementia. Little is known
about mixed pathologies in probable Alzheimer disease (AD) and about the spectrum of …

Clinical symptoms in Alzheimer's disease

OL López, ST DeKosky - Handbook of clinical neurology, 2008 - Elsevier
Publisher Summary This chapter describes that Alzheimer's disease (AD) is the most
prevalent form of dementia in individuals age 65 and older. The pathological substrate of the …

The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic …

GM McKhann, DS Knopman, H Chertkow… - Alzheimer's & …, 2011 - Elsevier
The National Institute on Aging and the Alzheimer's Association charged a workgroup with
the task of revising the 1984 criteria for Alzheimer's disease (AD) dementia. The workgroup …