Crosstalk between mitochondrial (dys) function and mitochondrial abundance

S Michel, A Wanet, A De Pauw… - Journal of cellular …, 2012 - Wiley Online Library
A controlled regulation of mitochondrial mass through either the production (biogenesis) or
the degradation (mitochondrial quality control) of the organelle represents a crucial step for …

Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis

K Palikaras, E Lionaki, N Tavernarakis - Cell Death & Differentiation, 2015 - nature.com
Mitochondria, the main energy hub of the cell, are highly dynamic organelles, playing
essential roles in fundamental cellular processes. Mitochondrial function impinges on …

Mitochondria in health and diseases

S Javadov, AV Kozlov, AKS Camara - Cells, 2020 - mdpi.com
Mitochondria are subcellular organelles evolved by endosymbiosis of bacteria with
eukaryotic cells characteristics. They are the main source of ATP in the cell and play a …

Mitochondrial biogenesis: An update

LD Popov - Journal of cellular and molecular medicine, 2020 - Wiley Online Library
In response to the energy demand triggered by developmental signals and environmental
stressors, the cells launch the mitochondrial biogenesis process. This is a self‐renewal …

[HTML][HTML] Mitochondria as intracellular signalling organelles. An update

LD Popov - Cellular Signalling, 2023 - Elsevier
Traditionally, mitochondria are known as" the powerhouse of the cell," responsible for
energy (ATP) generation (by the electron transport chain, oxidative phosphorylation, the …

[HTML][HTML] Mitochondrial quality control as a key determinant of cell survival

L Sedlackova, VI Korolchuk - … et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
Mitochondria are the energy producing dynamic double-membraned organelles essential
for cellular and organismal survival. A multitude of intra-and extra-cellular signals involved in …

Mitochondrial biogenesis and clearance: a balancing act

C Ploumi, I Daskalaki, N Tavernarakis - The FEBS journal, 2017 - Wiley Online Library
Mitochondria are semi‐autonomous organelles of prokaryotic origin that are postulated to
have been acquired by eukaryotic cells through an early endosymbiotic event. Except for …

Roles of mitochondria in human disease

MR Duchen, G Szabadkai - Essays in biochemistry, 2010 - portlandpress.com
The chapters throughout this volume illustrate the many contributions of mitochondria to the
maintenance of normal cell and tissue function, experienced as the health of the individual …

Mitochondria and autophagy: critical interplay between the two homeostats

K Okamoto, N Kondo-Okamoto - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
BACKGROUND: Mitochondria are dynamic organelles that frequently change their number,
size, shape, and distribution in response to intra-and extracellular cues. After proliferated …

[HTML][HTML] Mitochondrial dismissal in mammals, from protein degradation to mitophagy

S Campello, F Strappazzon, F Cecconi - Biochimica et Biophysica Acta …, 2014 - Elsevier
Mitochondria are double-membraned highly dynamic organelles; the shape, location and
function of which are determined by a constant balance between opposing fusion and …