Aims/hypothesis: We assessed how the role of genes genetic causation in causing maturity-
onset diabetes of the young (MODY) alters the response to an oral glucose tolerance test …

Mutations in the beta-cell genes encoding the glycolytic enzyme glucokinase (GCK) and the
transcription factor hepatocyte nuclear factor (HNF)-1alpha are the most common causes of …

Maturity‐onset diabetes of the young (MODY) can be defined by the clinical characteristics
of early‐onset Type 2 (non‐insulin‐dependent) diabetes and autosomal dominant …

Maturity-onset diabetes of the young (MODY) is a genetic subgroup of diabetes
characterised by an autosomal dominant inheritance and early onset, non-insulin …

Objective To investigate the frequencies of the major maturity-onset diabetes of the young
(MODY) subtypes in a panel of Spanish families and to assess phenotypic differences in …

Maturity-onset diabetes of the young (MODY) is a monogenic disorder that results in a
familial, young-onset non-insulin dependent form of diabetes, typically presenting in lean …

Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of
disorders characterized by nonketotic diabetes mellitus, an autosomal dominant mode of …

In Caucasians, maturity-onset diabetes of the young (MODY) is mostly caused by mutations
in the hepatocyte nuclear factor (HNF)-1α (MODY3) and glucokinase (MODY2) genes. Most …

Maturity-onset diabetes of the young is a heterogeneous group of autosomal dominantly
inherited, young-onset β-cell disorders. At least two consecutive generations are affected …

Genetic factors play an important role in various forms of diabetes mellitus (DM), but
inheritance is complex and interacts with environmental factors. Although in most cases type …