Despite substantial progress in understanding the cancer-signaling network, effective
therapies remain scarce due to insufficient disruption of oncogenic pathways, drug …

During the last decades, basic and translational research has enabled great improvements
in the clinical management of cancer. However, scarcity of complete remission and many …

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …

Within the last 15 years, microRNAs (miRNAs) have emerged as powerful regulators of gene
expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of …

Simple Summary Over the last few years, we have witnessed incredible advancements in
anti-tumor drug development. microRNAs, a class of small non-coding RNAs dysregulated …

Introduction: MicroRNAs (miRNAs) are a class of endogenous, non-coding small RNAs that
negatively regulate gene expression at the post-transcriptional level. Several studies have …

MiRNAs are a class of small, naturally occurring RNA molecules that play critical roles in
modulating numerous biological pathways by regulating gene expression. The knowledge …

The study of a class of small non-coding RNA molecules, named microRNAs (miRNAs), has
advanced our understanding of many of the fundamental processes of cancer biology and …

Tremendous progress has been made during the last few years in identification of novel
tumor-associated microRNAs and experimental validation of their cancer relevant gene …

Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the
expression of their target genes by reducing mRNA stability and/or inhibiting translation …