Amyloidosis is a heterogeneous group of protein misfolding diseases characterized by
deposition of amyloid proteins. The kidney is frequently affected, especially by …

Aims Identification and characterisation of monoclonal gammopathies of renal significance
(MGRS) is critical for therapeutic purposes. Amyloidosis represents one of the most common …

Background and objectives: Amyloidosis is a group of disorders characterized by
accumulation of extracellular deposition of proteins as insoluble aggregates. The clinical …

Background Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has recently
been utilized to accurately detect the amyloid proteins of renal amyloidosis. The present …

Amyloidosis is an uncommon disease that is characterized by abnormal extracellular
deposition of misfolded protein fibrils leading to organ dysfunction. The deposited proteins …

Amyloidosis is a shared name for several rare, complex and serious diseases caused by
extra-cellular deposits of different misfolded proteins. Accurate characterization of the …

The amyloidoses are a 'group'of disorders, all of which are associated with deposits that
display similar staining and ultrastructural features and are toxic to tissues. Many proteins …

The mechanisms of tissue damage in kidney amyloidosis are not well described. To
investigate this further, we used laser microdissection-mass spectrometry to identify proteins …

The tissue diagnosis of amyloidosis and confirmation of fibril protein type, which are crucial
for clinical management, have traditionally relied on Congo red (CR) staining followed by …

Amyloidosis is a group of diseases caused by extracellular accumulation of fibrillar
polypeptide aggregates. So far, diagnosis is performed by Congo red staining of tissue …