Valve replacement is the main therapy for valvular heart disease, in which a diseased valve
is replaced by mechanical heart valve (MHV) or bioprosthetic heart valve (BHV). Since the …

Despite the significant advances in cardiac surgery, heart valve replacement still faces a
dilemma. While mechanical valves offer lifelong durability they also commit patients to …

Surgical replacement with artificial devices has revolutionised the care of patients with
severe valvular diseases. Mechanical valves are very durable, but require long-term …

Bioprosthetic heart valves (BHVs) largely circumvent the need for long‐term anticoagulation
compared with mechanical valves but are increasingly susceptible to deterioration and …

Background Bioprosthetic heart valves (BHVs), fabricated from glutaraldehyde‐pretreated
bovine pericardium or porcine aortic valves, are widely used for the surgical or interventional …

The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment
of choice in patients requiring heart valve replacement surgery. Unlike mechanical heart …

Background Whereas the risk factors for structural valve degeneration (SVD) of
glutaraldehyde‐treated bioprosthetic heart valves (BHVs) are well studied, those …

Aortic valve calcification can aggravate aortic stenoses, and it is a significant cause of
sudden cardiac death. The increasing number of patients with age-related calcification is a …

Valvular heart diseases are associated with significant cardiovascular morbidity and
mortality, and often require surgical and/or percutaneous repair or replacement. Valve …

Pathologic calcification of implants is a detrimental condition that can severely impact device
performance and ultimately lead to implant failure. Although calcification affects a wide …