Eight psoralens have been evaluated for their ability to inhibit the in vitro growth of three
human tumor cell lines representing different tumor types, MCF-7 (breast cancer), NCI-H460 …

New tetracyclic benzofurocoumarin (benzopsoralen) analogues were synthesized and their
inhibitory effect on the growth of tumor cell lines was evaluated. The human tumor cell lines …

The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is
described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB …

In this review we summarize the structure and biological effects of linear and angular
psoralens. These compounds exhibit very interesting biological effects on cell cycle …

Coumarin belongs to a class of lactones that are fundamentally comprised of a benzene ring
fused to an α-pyrone ring; these lactones are known as benzopyrones. Similarly, coumarin …

Since long ago, medicinal plants have played a vital role in drug discovery. Being blessed
and rich in chemovars with diverse scaffolds, they have unique characteristics of evolving …

The QSAR directed synthesis of tetracyclic psoralen derivatives (3–5) characterised by the
condensation of a cyclopentane ring at the level of the 3, 4 double bond of the tricyclic …

Psoralen or furocoumarin is a linear three ring heterocyclic compound. Psoralens are
planar, tricyclic compounds, consisting of a furan ring fused to a coumarin moiety. Psoralen …

This review examines the biological properties of coumarins, widely distributed at the
highest levels in the fruit, followed by the roots, stems and leaves, by considering their …

This study reports the synthesis of tetrahydrobenzo-(4− 6) and benzopsoralen (7− 9)
derivatives obtained by condensing the fourth ring to the pyrone side of the tricyclic psoralen …