R Rossi, M Konar, PT Beernink - Infection and Immunity, 2016 - Am Soc Microbiol
Neisseria meningitidis causes cases of bacterial meningitis and sepsis. Factor H binding protein (FHbp) is a component of two licensed meningococcal serogroup B vaccines. FHbp …
S Principato, M Pizza, R Rappuoli - FEBS letters, 2020 - Wiley Online Library
Factor H binding protein (fHbp) is a key virulence factor of Neisseria meningitidis and a main component of the two licensed vaccines against serogroup B meningococcus (Bexsero and …
LK McNeil, RJ Zagursky, SL Lin, E Murphy… - Microbiology and …, 2013 - Am Soc Microbiol
Neisseria meningitidis is a Gram-negative microorganism that exists exclusively in humans and can cause devastating invasive disease. Although capsular polysaccharide-based …
PT Beernink, J Shaughnessy, S Ram… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
Meningococcal factor H-binding protein (fHbp) is a promising antigen that is part of two vaccines in clinical development. The protein specifically binds human complement factor H …
Background Meningococcal factor H binding protein (fHbp) is a promising vaccine candidate. Anti-fHbp antibodies can bind to meningococci and elicit complement-mediated …
S van der Veen, S Johnson, I Jongerius… - Infection and …, 2014 - Am Soc Microbiol
Neisseria meningitidis is a human-specific pathogen and leading cause of meningitis and septicemia. Factor H binding protein (fHbp), a virulence factor which protects N. meningitidis …
PT Beernink, J Shaughnessy, H Stefek… - Clinical and Vaccine …, 2014 - Am Soc Microbiol
Neisseria meningitidis causes disease only in humans. An important mechanism underlying this host specificity is the ability of the organism to resist complement by recruiting the …
Abstract Background. Factor H (fH) binding protein (fHbp) is part of vaccines developed for prevention of meningococcal serogroup B disease. More than 610 fHbp amino acid …
WX Yee, G Barnes, H Lavender, CM Tang - Trends in Microbiology, 2023 - cell.com
Neisseria meningitidis is a human-adapted pathogen that causes meningitis and sepsis worldwide. N. meningitidis factor H-binding protein (fHbp) provides a mechanism for …