Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro
Babesia (B.) bovis is one of the main etiological agents of bovine babesiosis, causes serious
economic losses to the cattle industry. Control of bovine babesiosis has been hindered by …
economic losses to the cattle industry. Control of bovine babesiosis has been hindered by …
Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds
In the present study, we screened 502 natural product compounds against the in vitro growth
of Babesia (B.) bovis. Then, the novel and potent identified compounds were further …
of Babesia (B.) bovis. Then, the novel and potent identified compounds were further …
Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis
NM Cardillo, PA Lacy, NF Villarino… - Frontiers in …, 2024 - frontiersin.org
Introduction: B. bovis is an apicomplexan parasite responsible for bovine babesiosis, a tick-
borne disease with a worldwide impact. The disease remains inefficiently controlled, and …
borne disease with a worldwide impact. The disease remains inefficiently controlled, and …
[HTML][HTML] The Combination of Buparvaquone and ELQ316 Exhibit a Stronger Effect than ELQ316 and Imidocarb Against Babesia bovis In Vitro
NM Cardillo, NF Villarino, PA Lacy, MK Riscoe… - Pharmaceutics, 2024 - mdpi.com
Background/Objectives: Bovine babesiosis is a vector-borne disease transmitted by ticks
that causes important losses in livestock worldwide. Recent research performed on the …
that causes important losses in livestock worldwide. Recent research performed on the …
In vitro screening of novel anti-Babesia gibsoni drugs from natural products
Babesia gibsoni is a tick-transmitted intraerythrocytic apicomplexan parasite that causes
babesiosis in dogs. Due to the strong side effects and lack of efficacy of current drugs, novel …
babesiosis in dogs. Due to the strong side effects and lack of efficacy of current drugs, novel …
Discovering the in vitro potent inhibitors against Babesia and Theileria parasites by repurposing the Malaria Box: A review
There is an innovative approach to discovering and developing novel potent and safe anti-
Babesia and anti-Theileria agents for the control of animal piroplasmosis. Large-scale …
Babesia and anti-Theileria agents for the control of animal piroplasmosis. Large-scale …
In vitro screening of compounds from the Food and Drug Administration-approved library identifies anti-Babesia gibsoni activity of idarubicin hydrochloride and …
Babesia gibsoni is mainly transmitted by hard ticks of the genus Rhipicephalus (R.
sanguineus) and Haemaphysalis (H. longicornis), and causes canine babesiosis. Clinical …
sanguineus) and Haemaphysalis (H. longicornis), and causes canine babesiosis. Clinical …
Inhibitory effects on bovine babesial infection by iron chelator, 1-(N-acetyl-6-aminohexyl)− 3-hydroxy-2-methylpyridin-4-one (CM1), and antimalarial drugs
P Koonyosying, S Srichairatanakool… - Veterinary …, 2023 - Elsevier
Background Babesiosis is an infectious disease caused by protozoa of the apicomplexan
phylum, genus Babesia. It is a malaria-like parasitic disease that can be transmitted via tick …
phylum, genus Babesia. It is a malaria-like parasitic disease that can be transmitted via tick …
Optimization of a Fluorescence-Based Assay for Large-Scale Drug Screening against Babesia and Theileria Parasites
A rapid and accurate assay for evaluating antibabesial drugs on a large scale is required for
the discovery of novel chemotherapeutic agents against Babesia parasites. In the current …
the discovery of novel chemotherapeutic agents against Babesia parasites. In the current …
Compounds from the Medicines for Malaria Venture Box Inhibit In Vitro Growth of Babesia divergens, a Blood-Borne Parasite of Veterinary and Zoonotic Importance
Babesiosis is an infectious disease with an empty drug pipeline. A search inside chemical
libraries for novel potent antibabesial candidates may help fill such an empty drug pipeline …
libraries for novel potent antibabesial candidates may help fill such an empty drug pipeline …