The synergistic hepatoprotective effect of curcumin and ginger against carbon tetrachloride induced-liver fibrosis in rats.

MK Ezz, GM Hamdy, RMA El-Atti - 2011 - cabidigitallibrary.org
The present study aimed to assess the hepatocellular protective activity of the co-
administration of curcumin fortified by ginger against carbon tetrachloride (CCl4)-induced …

Protective effects of curcumin and ginger on liver cirrhosis induced by carbon tetrachloride in rats.

GA Abd-Allah, KA El-Bakry, MH Bahnasawy… - 2016 - cabidigitallibrary.org
The aim of the present study is to investigate the protective effects of curcumin and/or ginger
against carbon tetrachloride (CCl4) induced hepatotoxicity. Therefore, 45 rats were divided …

[PDF][PDF] Antioxidant and anti-inflammatory effects of curcumin on CCl4–induced liver fibrosis in rats

NF Khedr, EG Khedr - Am. J. Biomed. Sci, 2014 - nwpii.com
Background: Liver fibrogenesis can lead to the development of cirrhosis and hepatocellular
carcinoma. This study was designed to evaluate the hepatoprotective effect of curcumin on …

Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats

MA Morsy, AM Abdalla, AM Mahmoud… - Journal of physiology …, 2012 - Springer
Liver fibrosis is a major health problem that can lead to the development of liver cirrhosis
and hepatocellular carcinoma. On the other hand, several antioxidants have been shown to …

Effects of curcumin on lipid profile and lipid peroxidation status in experimental hepatic fibrosis

G Akila, V Rajakrishnan, P Viswanathan… - Hepatology …, 1998 - Elsevier
Chronic administration of carbon tetrachloride caused liver fibrosis in rats. Carbon
tetrachloride-induced fibrosis was found to significantly elevate the marker enzymes, serum …

[PDF][PDF] Combined effect of curcumin and vitamin E against CCl4 induced liver injury in rats

V Gangarapu, S Gujjala, R Korivi, I Pala - Am J Life Sci, 2013 - researchgate.net
The present study was aimed to investigate the combined effect of curcumin [CMN] and
vitamin E against CCl4 induced oxidative stress and liver toxicity in rats. The toxicant CCl4 …

Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

C Tu, Q Yao, B Xu, J Wang, C Zhou, S Zhang - Food and chemical …, 2012 - Elsevier
The aim of the study was to investigate the effect of curcumin on the liver fibrosis induced by
carbon tetrachloride (CCl4) in rats, and to elucidate its underlying molecular mechanisms …

Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells

JC Shu, YJ He, X Lv, GR Ye, LX Wang - Journal of natural medicines, 2009 - Springer
This study was designed to investigate the prophylactic effects and the mechanisms of
curcumin on liver fibrosis in rats. Liver fibrosis was induced in 72 Sprague Dawley rats by …

Comparative effects of curcumin and an analogue of curcumin in carbon tetrachloride‐induced hepatotoxicity in rats

N Kamalakkannan, R Rukkumani… - Basic & clinical …, 2005 - Wiley Online Library
We have evaluated the comparative effect of curcumin (diferuloyl methane) and its analogue
[bis‐1, 7‐(2‐hydroxyphenyl)‐hepta‐1, 6‐diene‐3, 5‐dione](BDMC‐A) on carbon …

Curcumin protects against acute liver damage in the rat by inhibiting NF-κB, proinflammatory cytokines production and oxidative stress

K Reyes-Gordillo, J Segovia, M Shibayama… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Curcumin, an anti-inflammatory and antioxidant compound, was evaluated for its ability to
suppress acute carbon tetrachloride-induced liver damage. Acute hepatotoxicity was …