Associations between homocysteine, folic acid, vitamin B12 and Alzheimer's disease: insights from meta-analyses

L Shen, HF Ji - Journal of Alzheimer's Disease, 2015 - content.iospress.com
The associations between homocysteine (Hcy), folic acid, and vitamin B12 and Alzheimer's
disease (AD) have gained much interest, while remaining controversial. We aim to perform …

Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study

H Chen, S Liu, L Ji, T Wu, F Ma, Y Ji… - Current Alzheimer …, 2015 - ingentaconnect.com
Background: There is a growing focus on nutritional therapy for Alzheimer's disease (AD),
and controversy exists regarding the association between AD and homocysteine (Hcy) …

Homocysteine and folic acid: risk factors for Alzheimer's disease—an updated Meta-analysis

Q Wang, J Zhao, H Chang, X Liu, R Zhu - Frontiers in aging …, 2021 - frontiersin.org
Background: Recent studies have reported that homocysteine (Hcy) may play a vital role in
the pathogenesis of vascular dementia (VaD) and Alzheimer's disease (AD). Our study …

Hyperhomocysteinemia and Alzheimer's disease: A systematic review

F Van Dam, WA Van Gool - Archives of gerontology and geriatrics, 2009 - Elsevier
Hyperhomocysteinemia (HHcy) is supposed to be one of the modifiable risk factors that, if
treated, may delay the onset of Alzheimer's disease (AD). The relation between serum …

Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants

DS Wald, A Kasturiratne, M Simmonds - Alzheimer's & Dementia, 2011 - Elsevier
BACKGROUND: Prospective cohort studies have not been consistent in showing an
association between serum homocysteine and dementia. OBJECTIVE: To conduct a meta …

Plasma Homocysteine and Serum Folate and Vitamin B12 Levels in Mild Cognitive Impairment and Alzheimer's Disease: A Case-Control Study

F Ma, T Wu, J Zhao, L Ji, A Song, M Zhang, G Huang - Nutrients, 2017 - mdpi.com
Homocysteine (Hcy) is a risk factor for brain atrophy, cognitive impairment, and dementia.
Vitamin B12 and folate are cofactors necessary for the methylation of Hcy. However, there is …

Serum Homocysteine, Vitamin B 12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia

Y Song, M Quan, T Li, J Jia - Journal of Alzheimer's Disease, 2022 - content.iospress.com
Background: Although elevated levels of homocysteine (Hcy) are associated with cognitive
impairment and dementia, the relevance of Hcy, vitamin B12, and folate levels to subtypes of …

B-vitamins and prevention of dementia: Plenary Lecture

R Clarke - Proceedings of the Nutrition Society, 2008 - cambridge.org
Elevated plasma homocysteine (Hcy) concentrations have been implicated with risk of
cognitive impairment and dementia, but it is unclear whether low vitamin B12 or folate status …

Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study

B Hooshmand, A Solomon, I Kåreholt, J Leiviskä… - Neurology, 2010 - AAN Enterprises
Objective: To examine the relation between serum levels of homocysteine (tHcy) and
holotranscobalamin (holoTC), the active fraction of vitamin B12, and risk of incident …

Homocysteine and Alzheimer's disease: evidence for a causal link from Mendelian randomization

Q Hu, W Teng, J Li, F Hao… - Journal of Alzheimer's …, 2016 - content.iospress.com
Background/Objective: The relationship between plasma homocysteine (Hcy) levels and
Alzheimer's disease (AD) has been studied for many years, but remains controversial. While …