NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers

SJB Vos, BA Gordon, Y Su, PJ Visser, DM Holtzman… - Neurobiology of …, 2016 - Elsevier
Abstract The National Institute of Aging and Alzheimer's Association (NIA-AA) criteria for
Alzheimer disease (AD) treat neuroimaging and cerebrospinal fluid (CSF) markers of AD …

An operational approach to National Institute on Aging–Alzheimer's Association criteria for preclinical Alzheimer disease

CR Jack Jr, DS Knopman, SD Weigand… - Annals of …, 2012 - Wiley Online Library
Objective: A workgroup commissioned by the Alzheimer's Association (AA) and the National
Institute on Aging (NIA) recently published research criteria for preclinical Alzheimer disease …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Brain injury biomarkers are not dependent on β‐amyloid in normal elderly

DS Knopman, CR Jack Jr, HJ Wiste… - Annals of …, 2013 - Wiley Online Library
Objective The new criteria for preclinical Alzheimer disease (AD) proposed 3 stages:
abnormal levels of β‐amyloid (stage 1), stage 1 plus evidence of brain injury (stage 2), and …

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

DS Knopman, CR Jack Jr, HJ Wiste, SD Weigand… - Neurology, 2012 - AAN Enterprises
Objective: Recommendations for the diagnosis of preclinical Alzheimer disease (AD) have
been formulated by a workgroup of the National Institute on Aging and Alzheimer's …

Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum

DS Knopman, CR Jack Jr, ES Lundt, SD Weigand… - Neurobiology of …, 2016 - Elsevier
The availability of antemortem biomarkers for Alzheimer's disease (AD) enables monitoring
the evolution of neurodegenerative processes in real time. Pittsburgh compound B (PIB) …

Limited agreement between biomarkers of neuronal injury at different stages of Alzheimer's disease

P Alexopoulos, L Kriett, B Haller, E Klupp… - Alzheimer's & …, 2014 - Wiley Online Library
New diagnostic criteria for Alzheimer's disease (AD) treat different biomarkers of neuronal
injury as equivalent. Here, we quantified the degree of agreement between hippocampal …

Cognitive and brain profiles associated with current neuroimaging biomarkers of preclinical Alzheimer's disease

FL Besson, R La Joie, L Doeuvre… - Journal of …, 2015 - Soc Neuroscience
Neuroimaging biomarkers, namely hippocampal volume loss, temporoparietal
hypometabolism, and neocortical β-amyloid (Aβ) deposition, are included in the recent …

Biomarkers of Alzheimer disease: current and future applications to diagnostic criteria

R Sperling, K Johnson - CONTINUUM: Lifelong learning in …, 2013 - journals.lww.com
Abstract Purpose of Review: This article reviews recent advances in imaging and fluid
biomarkers for Alzheimer disease (AD) and their application to newly proposed diagnostic …