Comparing experimental design schemes in predictive food microbiology: Optimal parameter estimation of secondary models

L Mertens, E Van Derlinden, JF Van Impe - Journal of Food Engineering, 2012 - Elsevier
In predictive food microbiology, full factorial designs are still more the rule than the
exception, despite the huge experimental workload and cost related to this method. In this …

Computing optimal dynamic experiments for model calibration in predictive microbiology

E BALSA‐CANTO, AA Alonso… - Journal of Food Process …, 2008 - Wiley Online Library
The potential of mathematical models describing the microbial behavior during food
processing and storage largely depends on their predictive capabilities and, in this concern …

The impact of experiment design on the parameter estimation of cardinal parameter models in predictive microbiology

E Van Derlinden, L Mertens, JF Van Impe - Food Control, 2013 - Elsevier
In predictive food microbiology, cardinal parameter models are often applied to describe the
effect of temperature, pH and/or water activity on the microbial growth rate. To identify the …

Introducing optimal experimental design in predictive modeling: A motivating example

KJ Versyck, K Bernaerts, AH Geeraerd… - International Journal of …, 1999 - Elsevier
Predictive microbiology emerges more and more as a rational quantitative framework for
predicting and understanding microbial evolution in food products. During the mathematical …

18 Development and application of predictive microbiology models in foods

F Pérez-Rodríguez - Mathematical and statistical methods in food …, 2013 - books.google.com
Predictive microbiology is a relatively novel scientific field belonging to food microbiology; it
is aimed at developing mathematical models that account for the effect of intrinsic and …

Optimal experiment design for cardinal values estimation: guidelines for data collection

K Bernaerts, KPM Gysemans, TN Minh… - International Journal of …, 2005 - Elsevier
Optimal experiment design for parameter estimation (OED/PE) is an interesting technique for
modelling practices when aiming for maximum parameter estimation accuracy. Nowadays …

Optimal temperature input design for estimation of the square root model parameters: parameter accuracy and model validity restrictions

K Bernaerts, RD Servaes, S Kooyman… - International Journal of …, 2002 - Elsevier
As part of the model building process, parameter estimation is of great importance in view of
accurate prediction making. Confidence limits on the predicted model output are largely …

Comparing design of experiments and optimal experimental design techniques for modelling the microbial growth rate under static environmental conditions

S Akkermans, P Nimmegeers, JF Van Impe - Food microbiology, 2018 - Elsevier
Building secondary models that describe the growth rate as a function of multiple
environmental conditions is often very labour intensive and costly. As such, the current …

On the design of optimal dynamic experiments for parameter estimation of a Ratkowsky-type growth kinetics at suboptimal temperatures

K Bernaerts, KJ Versyck, JF Van Impe - International journal of food …, 2000 - Elsevier
It is generally known that accurate model building, ie, proper model structure selection and
reliable parameter estimation, constitutes an essential matter in the field of predictive …

Practical application of dynamic temperature profiles to estimate the parameters of the square root model

K Grijspeerdt, K De Reu - International journal of food microbiology, 2005 - Elsevier
Optimal experimental design for parameter estimation (OED/PE) is a promising method to
improve parameter estimation accuracy and minimise experimental effort in the field of …