Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC v1. 0 BeadChip microarrays
W Zhang, JI Young, L Gomez, MA Schmidt… - Epigenetics, 2024 - Taylor & Francis
ABSTRACT DNA methylation (DNAm) plays a crucial role in a number of complex diseases.
However, the reliability of DNAm levels measured using Illumina arrays varies across …
However, the reliability of DNAm levels measured using Illumina arrays varies across …
Technical and biological sources of unreliability of Infinium probes on Illumina methylation microarrays
T Nazarenko, CD Vavourakis, A Jones, I Evans… - Clinical …, 2024 - Springer
Abstract The Illumina Methylation array platform has facilitated countless epigenetic studies
on DNA methylation (DNAme) in health and disease, yet relatively few studies have so …
on DNA methylation (DNAme) in health and disease, yet relatively few studies have so …
Technical variability across the 450K, EPICv1, and EPICv2 DNA methylation arrays: lessons learned for clinical and longitudinal studies
DNA methylation (DNAm) is the most commonly measured epigenetic mechanism in human
populations, with most studies using Illumina arrays to assess DNAm levels. In 2023 …
populations, with most studies using Illumina arrays to assess DNAm levels. In 2023 …
Reliability of DNA methylation measures using Illumina methylation BeadChip
Illumina BeadChips are widely utilized in epigenome-wide association studies (EWAS).
Several studies have reported that many probes on these arrays have poor reliability. Here …
Several studies have reported that many probes on these arrays have poor reliability. Here …
Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time
M Forest, KJ O'Donnell, G Voisin, H Gaudreau… - Epigenetics, 2018 - Taylor & Francis
Epigenome-wide association studies (EWAS) have focused primarily on DNA methylation as
a chemically stable and functional epigenetic modification. However, the stability and …
a chemically stable and functional epigenetic modification. However, the stability and …
Technical and biological sources of unreliability of Infinium probes on Illumina Methylation microarrays
T Nazarenko, CD Vavourakis, A Jones, I Evans… - bioRxiv, 2023 - biorxiv.org
ABSTRACT The Illumina Methylation array platform has facilitated countless epigenetic
studies on DNA methylation (DNAme) in health and disease, yet relatively few studies have …
studies on DNA methylation (DNAme) in health and disease, yet relatively few studies have …
[PDF][PDF] Navigating Illumina DNA methylation data: biology versus technical artefacts
S Glaser, H Kretzmer, IT Kolassa… - NAR Genomics and …, 2024 - academic.oup.com
Illumina-based BeadChip arrays have revolutionized genome-wide DNA methylation
profiling, pushing it into diagnostics. However, comprehensive quality assessment remains …
profiling, pushing it into diagnostics. However, comprehensive quality assessment remains …
Establishing an analytic pipeline for genome-wide DNA methylation
The need for research investigating DNA methylation (DNAm) in clinical studies has
increased, leading to the evolution of new analytic methods to improve accuracy and …
increased, leading to the evolution of new analytic methods to improve accuracy and …
Evaluation of the pooled sample method in Infinium MethylationEPIC BeadChip array by comparison with individual samples
Background The pooled sample method is used in epigenomic research and expression
analysis and is a cost-effective screening approach for small amounts of DNA. Evaluation of …
analysis and is a cost-effective screening approach for small amounts of DNA. Evaluation of …
The ENmix DNA methylation analysis pipeline for Illumina BeadChip and comparisons with seven other preprocessing pipelines
Background Illumina DNA methylation arrays are high-throughput platforms for cost-effective
genome-wide profiling of individual CpGs. Experimental and technical factors introduce …
genome-wide profiling of individual CpGs. Experimental and technical factors introduce …