Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

RS Pappas - Metallomics, 2011 - academic.oup.com
Biochemically and pathologically, there is strong evidence for both atopic and nonatopic
airway sensitization, hyperresponsiveness, and inflammation as a consequence of exposure …

Toxicity of trace elements in tobacco smoke

SJSDBM Bagchi - Inhalation Toxicology, 1997 - Taylor & Francis
The potential to cause cellular damage by metal ions in conjunction with other constituents
of tobacco smoke is enormous. Various studies have demonstrated the role of reactive …

Pro-inflammatory effects of metals in persons and animals exposed to tobacco smoke

H Milnerowicz, M Ściskalska, M Dul - … of Trace Elements in Medicine and …, 2015 - Elsevier
Metals present in tobacco smoke have the ability to cause a pro-oxidant/antioxidant
imbalance through the direct generation of free radicals in accordance with the Fenton or …

Metals in cigarette smoke

D Bernhard, A Rossmann, G Wick - IUBMB life, 2005 - Wiley Online Library
Metals are vital for a huge number of physiological processes in the human body, but can
also destroy health when the concentration is not within the physiologically favourable …

Toxic metals in cigarettes and human health risk assessment associated with inhalation exposure

NU Benson, WU Anake, AE Adedapo… - Environmental …, 2017 - Springer
This study evaluated the concentrations of cadmium (Cd), copper (Cu), iron (Fe),
manganese (Mn), lead (Pb), and zinc (Zn) in 10 branded cigarettes commonly consumed in …

Metals transfer from tobacco to cigarette smoke: Evidences in smokers' lung tissue

E Pinto, M Cruz, P Ramos, A Santos… - Journal of Hazardous …, 2017 - Elsevier
Tobacco use kills millions of people every year around the world. The current level of 11
metals in tobacco was determined and their transfer rate to cigarette smoke was calculated …

Lung carcinogenesis: pivotal role of metals in tobacco smoke

JC Stavrides - Free Radical Biology and Medicine, 2006 - Elsevier
Although significant progress has been made in unraveling the molecular mechanisms
responsible for tobacco smoke toxicity and carcinogenicity, only limited information is …

Source and health implications of high toxic metal concentrations in illicit tobacco products

WE Stephens, A Calder, J Newton - Environmental science & …, 2005 - ACS Publications
A significant flux of heavy metals, among other toxins, reaches the lungs through smoking.
Consequently, contaminated soil is usually avoided for tobacco cultivation. Here we …

An in vitro approach to assess the toxicity of inhaled tobacco smoke components: nicotine, cadmium, formaldehyde and urethane

D Balharry, K Sexton, KA BéruBé - Toxicology, 2008 - Elsevier
One of the first lines of defence to inhaled toxins is the barrier formed by the
tracheobronchial epithelium, making this the ideal region for studying the toxicity of inhaled …

Toxic metal concentrations in mainstream smoke from cigarettes available in the USA

RS Pappas, MR Fresquez, N Martone… - Journal of analytical …, 2014 - academic.oup.com
Public health officials and leaders of 168 nations have signaled their concern regarding the
health and economic impacts of smoking by becoming signatory parties to the World Health …