Treating moderate plaque psoriasis: prospective 6-month chart review of patients treated with apremilast

MLF Knuckles, E Levi, J Soung - Journal of Dermatological …, 2019 - Taylor & Francis
Purpose: Apremilast, an oral phosphodiesterase 4 inhibitor, was effective in clinical trials in
patients with moderate plaque psoriasis (affected body surface area [BSA] 5% to 10%) …

Efficacy and safety of apremilast monotherapy for moderate to severe psoriasis: retrospective study

A Ighani, JR Georgakopoulos, LL Zhou… - Journal of …, 2018 - journals.sagepub.com
Background: Apremilast is a new oral drug for the treatment of moderate to severe plaque
psoriasis that reduces inflammation by inhibiting phosphodiesterase 4. Its efficacy and safety …

Long-term effectiveness and drug survival of apremilast in treating psoriasis: a real-world experience

J Distel, S Cazzaniga, SM Seyed Jafari, V Emelianov… - Dermatology, 2022 - karger.com
Background: Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor used for the
treatment of moderate to severe psoriasis. Long-term data on the effectiveness and drug …

Efficacy and Safety of Apremilast in Systemic-and Biologic-Naive Patients With Moderate Plaque Psoriasis: 52-Week Results of UNVEIL.

J Bagel, M Lebwohl, JM Jackson, R Chen… - Journal of drugs in …, 2018 - europepmc.org
BACKGROUND: Many patients with moderate plaque psoriasis are undertreated despite
broadening treatment options. In the phase IV UNVEIL study, oral apremilast demonstrated …

[HTML][HTML] Long-term safety and tolerability of apremilast in patients with psoriasis: Pooled safety analysis for≥ 156 weeks from 2 phase 3, randomized, controlled trials …

J Crowley, D Thaçi, P Joly, K Peris, KA Papp… - Journal of the american …, 2017 - Elsevier
Background Randomized, controlled trials demonstrated efficacy and safety of apremilast for
moderate-to-severe plaque psoriasis and psoriatic arthritis. Objective Assess long-term …

Efficacy and safety of apremilast in patients with moderate plaque psoriasis (UNVEIL phase 4 study)

B Strober, J Bagel, JM Lebwohl, L Stein Gold… - 2017 - scholarlycommons.henryford.com
Abstract Introduction and Objectives: Patients (pts) with moderate plaque psoriasis are often
inadequately treated (Armstrong, 2013), and there remains an unmet medical need for an …

Real-world experience with apremilast in treating psoriasis

JN Mayba, MJ Gooderham - Journal of cutaneous medicine …, 2017 - journals.sagepub.com
Background: Clinical trial data have shown apremilast, an oral phosphodiesterase-4
inhibitor, to be efficacious and safe for the treatment of psoriasis. However, little real-world …

Real‐world effectiveness and safety of apremilast in psoriasis at 52 weeks: a retrospective, observational, multicentre study by the Spanish Psoriasis Group

E Del Alcázar, JA Suárez‐Pérez… - Journal of the …, 2020 - Wiley Online Library
Background Little has been published on the real‐world effectiveness and safety of
apremilast in psoriasis. Objectives To evaluate the effectiveness, safety and drug survival of …

[HTML][HTML] Improvement in scalp and nails with apremilast in patients with moderate plaque psoriasis naive to systemic and biologic therapy: 52-week results of the …

JM Jackson, A Alikhan, M Lebwohl… - 2018 - scholarlycommons.henryford.com
Background/Objective: Patients with moderate plaque psoriasis (ie, 5–10% psoriasis-
involved Body Surface Area [BSA]) often receive no treatment or are undertreated with …

[HTML][HTML] Treatment persistence and safety of Apremilast in psoriasis: experience with 30 patients in routine clinical practice

A Sahuquillo-Torralba, B de Unamuno Bustos… - Actas Dermo …, 2020 - Elsevier
Apremilast is a phosphodiesterase-4 inhibitor taken orally. Little information about its use in
routine clinical practice is available. We aimed to assess treatment safety and persistence …