[HTML][HTML] Sweetspot mapping in deep brain stimulation: strengths and limitations of current approaches

TA Dembek, JC Baldermann… - … : Technology at the …, 2022 - Elsevier
Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain
stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different …

EEG-based biomarkers for optimizing deep brain stimulation contact configuration in Parkinson's disease

J Peeters, T Van Bogaert, A Boogers… - Frontiers in …, 2023 - frontiersin.org
Objective Subthalamic deep brain stimulation (STN-DBS) is a neurosurgical therapy to treat
Parkinson's disease (PD). Optimal therapeutic outcomes are not achieved in all patients due …

Programming of subthalamic nucleus deep brain stimulation for Parkinson's disease with sweet spot-guided parameter suggestions

S Nordenström, K Petermann, I Debove… - Frontiers in human …, 2022 - frontiersin.org
Deep Brain Stimulation (DBS) is an effective treatment for advanced Parkinson's disease.
However, identifying stimulation parameters, such as contact and current amplitudes, is time …

Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Directional stimulation of subthalamic nucleus sweet spot predicts clinical efficacy: proof of concept

TAK Nguyen, A Nowacki, I Debove, K Petermann… - Brain stimulation, 2019 - Elsevier
Background Directional deep brain stimulation (dDBS) of the subthalamic nucleus for
Parkinson's disease (PD) increases the therapeutic window. However, empirical …

Probabilistic analysis of activation volumes generated during deep brain stimulation

CR Butson, SE Cooper, JM Henderson, B Wolgamuth… - Neuroimage, 2011 - Elsevier
Deep brain stimulation (DBS) is an established therapy for the treatment of Parkinson's
disease (PD) and shows great promise for the treatment of several other disorders …

Model-based deep brain stimulation programming for Parkinson's disease: the GUIDE pilot study

MH Pourfar, AY Mogilner, S Farris, M Giroux… - Stereotactic and …, 2015 - karger.com
Background: Achieving optimal results following deep brain stimulation (DBS) typically
involves several months of programming sessions. The Graphical User Interface for DBS …

Probabilistic sweet spots predict motor outcome for deep brain stimulation in Parkinson disease

TA Dembek, J Roediger, A Horn, P Reker… - Annals of …, 2019 - Wiley Online Library
Objective To investigate whether functional sweet spots of deep brain stimulation (DBS) in
the subthalamic nucleus (STN) can predict motor improvement in Parkinson disease (PD) …

[HTML][HTML] Atlas-independent, N-of-1 tissue activation modeling to map optimal regions of subthalamic deep brain stimulation for Parkinson disease

KA Malaga, JT Costello, KL Chou, PG Patil - NeuroImage: Clinical, 2021 - Elsevier
Background Motor outcomes after subthalamic deep brain stimulation (STN DBS) for
Parkinson disease (PD) vary considerably among patients and strongly depend on …

An update on best practice of deep brain stimulation in Parkinson's disease

CJ Hartmann, S Fliegen, SJ Groiss… - Therapeutic …, 2019 - journals.sagepub.com
During the last 30 years, deep brain stimulation (DBS) has evolved into the clinical standard
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …