[PDF][PDF] Antioxidant and anti-inflammatory effects of curcumin on CCl4–induced liver fibrosis in rats

NF Khedr, EG Khedr - Am. J. Biomed. Sci, 2014 - nwpii.com
Background: Liver fibrogenesis can lead to the development of cirrhosis and hepatocellular
carcinoma. This study was designed to evaluate the hepatoprotective effect of curcumin on …

Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF‐β modulation and oxidative stress

K Reyes‐Gordillo, J Segovia… - Fundamental & …, 2008 - Wiley Online Library
Curcumin is a phytophenolic compound, which is highly efficacious for treating several
inflammatory diseases. The aim of this study was to evaluate the efficacy of curcumin in …

The synergistic hepatoprotective effect of curcumin and ginger against carbon tetrachloride induced-liver fibrosis in rats.

MK Ezz, GM Hamdy, RMA El-Atti - 2011 - cabidigitallibrary.org
The present study aimed to assess the hepatocellular protective activity of the co-
administration of curcumin fortified by ginger against carbon tetrachloride (CCl4)-induced …

Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon …

Q Yao, B Xu, J Wang, H Liu, S Zhang, C Tu - BMC complementary and …, 2012 - Springer
Background At present there is no effective and accepted therapy for hepatic fibrosis.
Transforming growth factor (TGF)-β1 signaling pathway contributes greatly to hepatic …

[PDF][PDF] Combined effect of curcumin and vitamin E against CCl4 induced liver injury in rats

V Gangarapu, S Gujjala, R Korivi, I Pala - Am J Life Sci, 2013 - researchgate.net
The present study was aimed to investigate the combined effect of curcumin [CMN] and
vitamin E against CCl4 induced oxidative stress and liver toxicity in rats. The toxicant CCl4 …

Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats

MA Morsy, AM Abdalla, AM Mahmoud… - Journal of physiology …, 2012 - Springer
Liver fibrosis is a major health problem that can lead to the development of liver cirrhosis
and hepatocellular carcinoma. On the other hand, several antioxidants have been shown to …

Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

C Tu, Q Yao, B Xu, J Wang, C Zhou, S Zhang - Food and chemical …, 2012 - Elsevier
The aim of the study was to investigate the effect of curcumin on the liver fibrosis induced by
carbon tetrachloride (CCl4) in rats, and to elucidate its underlying molecular mechanisms …

Immunomodulatory effect of curcumin on hepatic cirrhosis in experimental rats

MA Abo‐Zaid, ES Shaheen… - Journal of food …, 2020 - Wiley Online Library
Cirrhosis is a chronic liver disease. The present work aimed to evaluate the regulatory
immune effect of curcumin in hepatic cirrhosis induced by carbon tetrachloride (CCl4) …

Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells

JC Shu, YJ He, X Lv, GR Ye, LX Wang - Journal of natural medicines, 2009 - Springer
This study was designed to investigate the prophylactic effects and the mechanisms of
curcumin on liver fibrosis in rats. Liver fibrosis was induced in 72 Sprague Dawley rats by …

Acupuncture combined with curcumin attenuates carbon tetrachloride-induced hepatic fibrosis in rats

F Zhang, J Ma, Y Lu, GX Ni, CY Ni… - Acupuncture in …, 2012 - journals.sagepub.com
Background Increasingly, studies demonstrate the effectiveness of acupuncture therapy
against liver fibrosis. Curcumin is a natural product with antifibrotic effects, but has poor …