Electrospun fibro-porous polyurethane coatings for implantable glucose biosensors

N Wang, K Burugapalli, W Song, J Halls, F Moussy… - Biomaterials, 2013 - Elsevier
This study reports methods for coating miniature implantable glucose biosensors with
electrospun polyurethane (PU) membranes, their effects on sensor function and efficacy as …

Electrospun polyurethane-core and gelatin-shell coaxial fibre coatings for miniature implantable biosensors

N Wang, K Burugapalli, S Wijesuriya, MY Far… - …, 2013 - iopscience.iop.org
The aim of this study was to introduce bioactivity to the electrospun coating for implantable
glucose biosensors. Coaxial fibre membranes having polyurethane as the core and gelatin …

Biomimetic electrospun coatings increase the in vivo sensitivity of implantable glucose biosensors

K Burugapalli, S Wijesuriya, N Wang… - Journal of Biomedical …, 2018 - Wiley Online Library
In vivo tissue responses and functional efficacy of electrospun membranes based on
polyurethane (PU) and gelatin (GE) as biomimetic coatings for implantable glucose …

Porous, Dexamethasone-loaded polyurethane coatings extend performance window of implantable glucose sensors in vivo

SG Vallejo-Heligon, NL Brown, WM Reichert… - Acta biomaterialia, 2016 - Elsevier
Continuous glucose sensors offer the promise of tight glycemic control for insulin dependent
diabetics; however, utilization of such systems has been hindered by issues of tissue …

Tailored fibro-porous structure of electrospun polyurethane membranes, their size-dependent properties and trans-membrane glucose diffusion

N Wang, K Burugapalli, W Song, J Halls… - Journal of membrane …, 2013 - Elsevier
The aim of this study was to develop polyurethane (PU) based fibro-porous membranes and
to investigate the size-effect of hierarchical porous structure on permeability and surface …

A long-term flexible minimally-invasive implantable glucose biosensor based on an epoxy-enhanced polyurethane membrane

B Yu, N Long, Y Moussy, F Moussy - Biosensors and Bioelectronics, 2006 - Elsevier
This paper describes the preparation method as well as the in vitro and in vivo evaluation of
a novel flexible glucose biosensor designed for long-term subcutaneous implantation. An …

Characterization of porous, dexamethasone-releasing polyurethane coatings for glucose sensors

SG Vallejo-Heligon, B Klitzman, WM Reichert - Acta biomaterialia, 2014 - Elsevier
Commercially available implantable needle-type glucose sensors for diabetes management
are robust analytically but can be unreliable clinically primarily due to tissue–sensor …

Use of hydrogel coating to improve the performance of implanted glucose sensors

B Yu, C Wang, YM Ju, L West, J Harmon… - Biosensors and …, 2008 - Elsevier
In order to protect implanted glucose sensors from biofouling, novel hydrogels (146–217%
water by mass) were developed based on a copolymer of hydroxyethyl methacrylate …

Fabrication of nitric oxide-releasing porous polyurethane membranes-coated needle-type implantable glucose biosensors

A Koh, Y Lu, MH Schoenfisch - Analytical chemistry, 2013 - ACS Publications
The active release of pharmaceutical agents and the use of porous sensor membranes
represent the two most promising strategies for addressing the poor tissue biocompatibility …

PVDF-Nafion nanomembranes coated microneedles for in vivo transcutaneous implantable glucose sensing

D Chen, C Wang, W Chen, Y Chen… - Biosensors and …, 2015 - Elsevier
We demonstrate that microporous PVDF membranes sandwiched between multiple layers of
nanomaterials can be used for continuous monitoring of glucose level in vivo. This is …