The dihydropyridine derivatives CGP 28392 and BAY K 8644 exert a strong positive
inotropic effect in mammalian cardiac muscle, presumably by increasing Ca influx during the …

We have investigated the effects of two oppositely acting enantiomers of the 1, 4-
dihydropyridine derivative 202-791 on voltage-dependent Ca channels by combining …

We studied the effects of dihydropyridine Ca channel ligands (DHPs), mainly nitrendipine
and Bay K8644, on whole cell and single channel Ca currents on single myocytes isolated …

We have investigated the voltage-dependent effects of the dihydropyridine Bay K8644 on
Ca channel currents in calf Purkinje fibers and enzymatically dispersed rat ventricular …

This comparison of the binding characteristics and pharmacology of 1, 4‐dihydropyridines
indicates that the high‐affinity binding sites studied in cardiac and smooth muscle cells …

Bay k 8644 is a structural analog of nifedipine with positive inotropic activity. The mechanism
of drug action was evaluated by measuring the effects of Bay k 8644 on twitch tension …

To investigate the mechanism of action of dihydropyridines on calcium channels, both
receptor binding and the electrophysiological effects of optically pure enantiomers of Bay k …

The whole-cell patch-clamp technique has been used to analyze the properties of the
dihydropyridine-sensitive Ca2+ channel in rat skeletal muscle cells (myoballs) in culture …

Pharmacological studies have provided considerable information about the molecular
structure of ion channels in the membranes of excitable cells. Two classes of drugs, the local …

We have investigated the mechanisms of blockade of calcium channel current by the
dihydropyridines, eg nisoldipine, nitrendipine, and nicardipine. Membrane current was …