The orbitofrontal cortex (OFC) is critical for updating reward-directed behaviours flexibly
when outcomes are devalued or when task contingencies are reversed. Failure to update …

Abstract Evaluation of the behavioral 'costs', such as effort expenditure relative to the
benefits of obtaining reward, is a major determinant of goal‐directed action. Neuroimaging …

The orbitofrontal cortex (OFC) has been broadly implicated in the ability to use the current
value of expected outcomes to guide behavior. Although value correlates have been …

The orbitofrontal cortex (OFC) and basolateral amygdala (BLA) are critical for using learned
representations of outcomes to guide behavior. Neurophysiological findings suggest …

The lateral orbitofrontal cortex (lOFC) has been described as signaling either outcome
expectancies or value. Previously, we used unblocking to show that lOFC neurons respond …

The orbitofrontal cortex and adjacent ventromedial prefrontal cortex carry reward
representations and mediate flexible behaviour when circumstances change. Here we …

Outcome-guided behavior requires knowledge about the current value of expected
outcomes. Such behavior can be isolated in the reinforcer devaluation task, which assesses …

The precise role of orbitofrontal cortex (OFC) in affective processing is still debated. One
view suggests OFC represents stimulus reward value and supports learning and relearning …

Previous studies have implicated the orbitofrontal cortex (OFC) in outcome encoding.
However, it remains unknown whether the OFC is selectively involved in pavlovian stimulus …

Humans and other animals change their behavior in response to unexpected outcomes. The
orbitofrontal cortex (OFC) is implicated in such adaptive responding, based on evidence …