1. An increase in the rate of stimulation induces an augmentation of L‐type Ca2+ currents
(ICa) and concomitant slowing of current decay in rat ventricular cells. This facilitation is …

1 During an action potential the L‐type Ca2+ current (ICa, L) activates rapidly, then partially
declines leading to a sustained inward current during the plateau phase. The reason for the …

The modulation of L-type Ca2+ current (ICa) by changes in stimulation frequency was
investigated in single ventricular cardiomyocytes isolated from guinea pig hearts. Electrical …

1. The caged calcium compound nitr‐5 has been used to investigate the response of the L‐
type calcium current (ICa) of guinea‐pig ventricular cells to a rapid increase in the free …

The whole-cell patch-clamp technique was used to study the effects of holding potential and
frequency on the Ca 2+ current in frog ventricular myocytes. I Na was blocked by TTX, and i …

Abstract L-type Ca 2+ current, i Ca, has been recorded in guinea-pig ventricular myocytes at
36° C using the whole cell patch clamp technique. Intracellular Ca 2+ was buffered with …

1. Stimulation‐dependent modulation of Ca currents was examined in guinea‐pig
ventricular myocytes at room temperature. Whole‐cell recordings of Ca currents were made …

The objective of this study was to describe the kinetics of voltage‐dependent inactivation of
native cardiac L‐type Ca2+ currents. Whole‐cell currents were recorded from guinea‐pig …

1. Inactivation of Ca2+ current (ICa) induced by Ca2+ release from sarcoplasmic reticulum
(SR) was studied in single rat ventricular myocytes using whole‐cell patch‐clamp and indo …

1. High‐voltage‐activated Ca2+ current (ICa) waveforms in adult rat ventricular myocytes
comprise two components, referred to here as ICa (fc) and ICa (sc) to denote the fast and …